Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947475828> ?p ?o ?g. }
Showing items 1 to 52 of
52
with 100 items per page.
- W2947475828 abstract "e17069 Background: The objective of this study was to assess the factors associated with one-year mortality following cytoreductive surgery among women ≥65 years with epithelial ovarian cancer (EOC). Methods: Since 2011, patients aged 65 and older with advanced EOC, who underwent cytoreductive surgery within two months of initial visit, and had at least one year of follow up were included. Mortality data was retrieved from social security death index. Independent variables of interest were age, American Society of Anesthesiologist Physical Status (ASA-PS) classification, preoperative albumin, Memorial Sloan Kettering Frailty Index (MSK-FI), procedure time, intraoperative blood loss, 30-day minor and major adverse events, 30-day readmission and emergency room visits, stage, rate of suboptimal surgery, and receipt of neoadjuvant chemotherapy (NACT). Univariate analysis was performed to assess relationship between these variables and one-year mortality. Results: In total, 263 women (median age 70, range 65-88), of whom 26% had stage IV disease and 5% suboptimal surgery, were included. One-year mortality was 6.5% (n = 17), with six patients dying within six months. On univariate analysis, patients who died within the first year differed from those who were alive at one year in terms of length of stay (13 vs 9 days, p = 0.01), pre-operative albumin (3.8 vs 4.1, p = 0.01), major adverse events (29.4% vs. 12.2%, p = 0.04), and receipt of NACT (33.3% vs. 14.7%, p = 0.05). Patients who died within one year had an insignificant difference in MSK-FI (1.4 vs. 0.8, p = 0.08), and pre-operative hemoglobin (11.4 vs. 12.1, p = 0.06), as well as no difference in in age, ASA-PS, stage, procedure time, blood loss, minor adverse events, readmission and emergency room visits. Patients with suboptimal surgery did not have significantly higher one-year mortality rates, compared to those with optimal resection (11.8% vs. 4.5%, p = 0.5). Conclusions: Cytoreductive surgery in the selected group of older women is safe. In this cohort, age and ASA PS were not among factors associated with one year mortality. More robust risk stratification for this cohort is needed." @default.
- W2947475828 created "2019-06-07" @default.
- W2947475828 creator A5023125767 @default.
- W2947475828 creator A5023427533 @default.
- W2947475828 creator A5024962229 @default.
- W2947475828 creator A5031738512 @default.
- W2947475828 creator A5053852463 @default.
- W2947475828 creator A5067705220 @default.
- W2947475828 creator A5075806320 @default.
- W2947475828 creator A5077690076 @default.
- W2947475828 creator A5083345435 @default.
- W2947475828 date "2019-05-20" @default.
- W2947475828 modified "2023-09-23" @default.
- W2947475828 title "Factors associated with one-year mortality after debulking surgery in older women with ovarian cancer." @default.
- W2947475828 doi "https://doi.org/10.1200/jco.2019.37.15_suppl.e17069" @default.
- W2947475828 hasPublicationYear "2019" @default.
- W2947475828 type Work @default.
- W2947475828 sameAs 2947475828 @default.
- W2947475828 citedByCount "0" @default.
- W2947475828 crossrefType "journal-article" @default.
- W2947475828 hasAuthorship W2947475828A5023125767 @default.
- W2947475828 hasAuthorship W2947475828A5023427533 @default.
- W2947475828 hasAuthorship W2947475828A5024962229 @default.
- W2947475828 hasAuthorship W2947475828A5031738512 @default.
- W2947475828 hasAuthorship W2947475828A5053852463 @default.
- W2947475828 hasAuthorship W2947475828A5067705220 @default.
- W2947475828 hasAuthorship W2947475828A5075806320 @default.
- W2947475828 hasAuthorship W2947475828A5077690076 @default.
- W2947475828 hasAuthorship W2947475828A5083345435 @default.
- W2947475828 hasConcept C121608353 @default.
- W2947475828 hasConcept C126322002 @default.
- W2947475828 hasConcept C141071460 @default.
- W2947475828 hasConcept C143998085 @default.
- W2947475828 hasConcept C2780427987 @default.
- W2947475828 hasConcept C2781100745 @default.
- W2947475828 hasConcept C29456083 @default.
- W2947475828 hasConcept C71924100 @default.
- W2947475828 hasConceptScore W2947475828C121608353 @default.
- W2947475828 hasConceptScore W2947475828C126322002 @default.
- W2947475828 hasConceptScore W2947475828C141071460 @default.
- W2947475828 hasConceptScore W2947475828C143998085 @default.
- W2947475828 hasConceptScore W2947475828C2780427987 @default.
- W2947475828 hasConceptScore W2947475828C2781100745 @default.
- W2947475828 hasConceptScore W2947475828C29456083 @default.
- W2947475828 hasConceptScore W2947475828C71924100 @default.
- W2947475828 hasLocation W29474758281 @default.
- W2947475828 hasOpenAccess W2947475828 @default.
- W2947475828 hasPrimaryLocation W29474758281 @default.
- W2947475828 isParatext "false" @default.
- W2947475828 isRetracted "false" @default.
- W2947475828 magId "2947475828" @default.
- W2947475828 workType "article" @default.