Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947536735> ?p ?o ?g. }
- W2947536735 abstract "Abstract A shift in environmental conditions impacts the evolution of complex developmental and behavioral traits. The Mexican cavefish, Astyanax mexicanus , is a powerful model for examining the evolution of development, physiology, and behavior because multiple cavefish populations can be compared to an extant and ancestral-like surface population of the same species. Many behaviors have diverged in cave populations of A. mexicanus , and previous studies have shown that cavefish have a loss of sleep, reduced stress, an absence of social behaviors, and hyperphagia. Despite these findings, surprisingly little is known about the changes in neuroanatomy that underlie these behavioral phenotypes. Here, we use serial sectioning to generate a brain atlas of surface fish and three independent cavefish populations. Volumetric reconstruction of serial-sectioned brains confirms convergent evolution on reduced optic tectum volume in all cavefish populations tested. In addition, we quantified volumes of specific neuroanatomical loci within several brain regions, which have previously been implicated in behavioral regulation, including the hypothalamus, thalamus, and habenula. These analyses reveal an expansion of the hypothalamus across all three cavefish populations relative to surface fish, as well as subnuclei-specific differences within the thalamus and habenulae. Taken together, these analyses support the notion that changes in environmental conditions are accompanied by neuroanatomical changes in brain structures associated with behavior. This atlas provides a resource for comparative neuroanatomy of additional brain regions and the opportunity to associate brain anatomy with evolved changes in behavior." @default.
- W2947536735 created "2019-06-07" @default.
- W2947536735 creator A5005479991 @default.
- W2947536735 creator A5013601672 @default.
- W2947536735 creator A5029765045 @default.
- W2947536735 creator A5033001511 @default.
- W2947536735 creator A5036264319 @default.
- W2947536735 creator A5040198135 @default.
- W2947536735 creator A5041865755 @default.
- W2947536735 creator A5056103425 @default.
- W2947536735 creator A5068564206 @default.
- W2947536735 creator A5070126963 @default.
- W2947536735 creator A5079001963 @default.
- W2947536735 creator A5086115824 @default.
- W2947536735 creator A5089426522 @default.
- W2947536735 date "2019-05-27" @default.
- W2947536735 modified "2023-09-27" @default.
- W2947536735 title "An adult brain atlas reveals broad neuroanatomical changes in independently evolved populations of Mexican cavefish" @default.
- W2947536735 cites W14609908 @default.
- W2947536735 cites W148563325 @default.
- W2947536735 cites W1536195886 @default.
- W2947536735 cites W1862379064 @default.
- W2947536735 cites W1919935630 @default.
- W2947536735 cites W1964413276 @default.
- W2947536735 cites W1964763155 @default.
- W2947536735 cites W1965647283 @default.
- W2947536735 cites W1971978102 @default.
- W2947536735 cites W1976122633 @default.
- W2947536735 cites W1979606683 @default.
- W2947536735 cites W1990257951 @default.
- W2947536735 cites W1999919528 @default.
- W2947536735 cites W2005921367 @default.
- W2947536735 cites W2016117011 @default.
- W2947536735 cites W2018737563 @default.
- W2947536735 cites W2023461053 @default.
- W2947536735 cites W2027122337 @default.
- W2947536735 cites W2027131349 @default.
- W2947536735 cites W2031712485 @default.
- W2947536735 cites W2035699903 @default.
- W2947536735 cites W2038806095 @default.
- W2947536735 cites W2041641287 @default.
- W2947536735 cites W2043375438 @default.
- W2947536735 cites W2047578534 @default.
- W2947536735 cites W2052357348 @default.
- W2947536735 cites W2064194489 @default.
- W2947536735 cites W2066908868 @default.
- W2947536735 cites W2067565316 @default.
- W2947536735 cites W2076350171 @default.
- W2947536735 cites W2077079412 @default.
- W2947536735 cites W2087852288 @default.
- W2947536735 cites W2088231886 @default.
- W2947536735 cites W2089315051 @default.
- W2947536735 cites W2097821290 @default.
- W2947536735 cites W2097980270 @default.
- W2947536735 cites W2104101134 @default.
- W2947536735 cites W2104809172 @default.
- W2947536735 cites W2118417588 @default.
- W2947536735 cites W2120642897 @default.
- W2947536735 cites W2121937735 @default.
- W2947536735 cites W2131938193 @default.
- W2947536735 cites W2136820200 @default.
- W2947536735 cites W2137232941 @default.
- W2947536735 cites W2137316421 @default.
- W2947536735 cites W2137600012 @default.
- W2947536735 cites W2139044627 @default.
- W2947536735 cites W2141237174 @default.
- W2947536735 cites W2142943575 @default.
- W2947536735 cites W2145630843 @default.
- W2947536735 cites W2145926148 @default.
- W2947536735 cites W2146714846 @default.
- W2947536735 cites W2161254621 @default.
- W2947536735 cites W2166321828 @default.
- W2947536735 cites W2167279371 @default.
- W2947536735 cites W2171911690 @default.
- W2947536735 cites W2186694278 @default.
- W2947536735 cites W2191137763 @default.
- W2947536735 cites W2192544502 @default.
- W2947536735 cites W2195203628 @default.
- W2947536735 cites W2277956273 @default.
- W2947536735 cites W2310949909 @default.
- W2947536735 cites W2328427632 @default.
- W2947536735 cites W2413680873 @default.
- W2947536735 cites W2484659268 @default.
- W2947536735 cites W2558301331 @default.
- W2947536735 cites W2577666567 @default.
- W2947536735 cites W2729250854 @default.
- W2947536735 cites W2735498584 @default.
- W2947536735 cites W2782595494 @default.
- W2947536735 cites W2785754928 @default.
- W2947536735 cites W2801033181 @default.
- W2947536735 cites W2803758185 @default.
- W2947536735 cites W2803841419 @default.
- W2947536735 cites W2806176244 @default.
- W2947536735 cites W2906656539 @default.
- W2947536735 cites W2939912300 @default.
- W2947536735 cites W2949808130 @default.
- W2947536735 cites W2952378441 @default.
- W2947536735 cites W2952827404 @default.
- W2947536735 cites W2984625732 @default.
- W2947536735 cites W4237154700 @default.