Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947580953> ?p ?o ?g. }
- W2947580953 endingPage "939" @default.
- W2947580953 startingPage "939" @default.
- W2947580953 abstract "In the present study, poly(ethylene glycol)-b-poly(N,N-diethylaminoethyl methacrylate) (PEG-b-PDEAEM) amphiphilic block copolymers were synthetized by reversible addition-fragmentation chain transfer (RAFT) polymerization using two different macro chain transfer agents containing PEG of 2000 and 5000 g/mol and varying the length of the PDEAEM segment. From the obtained block copolymers, polymersome type nanometric aggregates were obtained by two different techniques. By direct dispersion, particle diameters around 200 nm were obtained, while by solvent exchange using THF and water, the obtained diameters were around 100 nm. These block copolymers were used to encapsulate gold nanorods and doxorubicin (DOX) with good efficiencies to obtain nanomaterials with potential use as dual stimuli-sensitive drug delivery systems for combined anticancer therapies. Drug delivery studies showed that the release rate of DOX was accelerated when the pH was lowered from 7.4 to 5.8 and also when the systems were irradiated with a NIR laser at pH 7.4. The combination of lower pH and near infrared (NIR) irradiation resulted in higher drug release only in the case of polymersomes with lower molecular weight PEG." @default.
- W2947580953 created "2019-06-07" @default.
- W2947580953 creator A5009192465 @default.
- W2947580953 creator A5019168407 @default.
- W2947580953 creator A5046079255 @default.
- W2947580953 creator A5047242952 @default.
- W2947580953 creator A5077316557 @default.
- W2947580953 date "2019-05-30" @default.
- W2947580953 modified "2023-10-18" @default.
- W2947580953 title "Dual Responsive Polymersomes for Gold Nanorod and Doxorubicin Encapsulation: Nanomaterials with Potential Use as Smart Drug Delivery Systems" @default.
- W2947580953 cites W1965251103 @default.
- W2947580953 cites W1970571815 @default.
- W2947580953 cites W1971455130 @default.
- W2947580953 cites W1972804296 @default.
- W2947580953 cites W1979849149 @default.
- W2947580953 cites W1982778919 @default.
- W2947580953 cites W1984233626 @default.
- W2947580953 cites W1988155694 @default.
- W2947580953 cites W1990076291 @default.
- W2947580953 cites W1990098432 @default.
- W2947580953 cites W1990851344 @default.
- W2947580953 cites W1993855084 @default.
- W2947580953 cites W2009597964 @default.
- W2947580953 cites W2040039765 @default.
- W2947580953 cites W2050061183 @default.
- W2947580953 cites W2052301068 @default.
- W2947580953 cites W2053678405 @default.
- W2947580953 cites W2056960929 @default.
- W2947580953 cites W2063705045 @default.
- W2947580953 cites W2079590454 @default.
- W2947580953 cites W2089073859 @default.
- W2947580953 cites W2092168785 @default.
- W2947580953 cites W2102492267 @default.
- W2947580953 cites W2104013724 @default.
- W2947580953 cites W2114939324 @default.
- W2947580953 cites W2120377744 @default.
- W2947580953 cites W2129166766 @default.
- W2947580953 cites W2158231500 @default.
- W2947580953 cites W2163818897 @default.
- W2947580953 cites W2163887121 @default.
- W2947580953 cites W2164338355 @default.
- W2947580953 cites W2298586992 @default.
- W2947580953 cites W2326573831 @default.
- W2947580953 cites W2517872912 @default.
- W2947580953 cites W2572630386 @default.
- W2947580953 cites W2573157670 @default.
- W2947580953 cites W2573184299 @default.
- W2947580953 cites W2588221525 @default.
- W2947580953 cites W2725461327 @default.
- W2947580953 cites W2744575417 @default.
- W2947580953 cites W2745835938 @default.
- W2947580953 cites W2752243232 @default.
- W2947580953 cites W2793176734 @default.
- W2947580953 cites W2800577867 @default.
- W2947580953 cites W2804706598 @default.
- W2947580953 cites W2898347319 @default.
- W2947580953 cites W2898597808 @default.
- W2947580953 cites W2900252775 @default.
- W2947580953 cites W2908757118 @default.
- W2947580953 cites W4212814362 @default.
- W2947580953 doi "https://doi.org/10.3390/polym11060939" @default.
- W2947580953 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6630455" @default.
- W2947580953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31151188" @default.
- W2947580953 hasPublicationYear "2019" @default.
- W2947580953 type Work @default.
- W2947580953 sameAs 2947580953 @default.
- W2947580953 citedByCount "21" @default.
- W2947580953 countsByYear W29475809532020 @default.
- W2947580953 countsByYear W29475809532021 @default.
- W2947580953 countsByYear W29475809532022 @default.
- W2947580953 countsByYear W29475809532023 @default.
- W2947580953 crossrefType "journal-article" @default.
- W2947580953 hasAuthorship W2947580953A5009192465 @default.
- W2947580953 hasAuthorship W2947580953A5019168407 @default.
- W2947580953 hasAuthorship W2947580953A5046079255 @default.
- W2947580953 hasAuthorship W2947580953A5047242952 @default.
- W2947580953 hasAuthorship W2947580953A5077316557 @default.
- W2947580953 hasBestOaLocation W29475809531 @default.
- W2947580953 hasConcept C111998727 @default.
- W2947580953 hasConcept C121120078 @default.
- W2947580953 hasConcept C127413603 @default.
- W2947580953 hasConcept C138631740 @default.
- W2947580953 hasConcept C15920480 @default.
- W2947580953 hasConcept C171250308 @default.
- W2947580953 hasConcept C178790620 @default.
- W2947580953 hasConcept C185592680 @default.
- W2947580953 hasConcept C192562407 @default.
- W2947580953 hasConcept C2777516009 @default.
- W2947580953 hasConcept C2779820397 @default.
- W2947580953 hasConcept C42360764 @default.
- W2947580953 hasConcept C51115888 @default.
- W2947580953 hasConcept C521977710 @default.
- W2947580953 hasConcept C67407626 @default.
- W2947580953 hasConcept C9132879 @default.
- W2947580953 hasConceptScore W2947580953C111998727 @default.
- W2947580953 hasConceptScore W2947580953C121120078 @default.
- W2947580953 hasConceptScore W2947580953C127413603 @default.
- W2947580953 hasConceptScore W2947580953C138631740 @default.