Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947657280> ?p ?o ?g. }
- W2947657280 endingPage "103021" @default.
- W2947657280 startingPage "103021" @default.
- W2947657280 abstract "Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic compound with wide ranges of pharmacological activities due to different mechanisms of action. It is an superlative moiety in drug discovery with the sole property of resembling different structures of the protein. Plenty of research has been taking place in recent years to synthesize and explore the various therapeutic prospectives of this moiety. This review summarizes some of the recent effective chemical synthesis (2014-2018) for indole ring. This review also emphasized on the structure-activity relationship (SAR) to reveal the active pharmacophores of various indole analogues accountable for anticancer, anticonvulsant, antimicrobial, antitubercular, antimalarial, antiviral, antidiabetic and other miscellaneous activities which have been investigated in the last five years. The precise features with motives and framework of each research topic is introduced for helping the medicinal chemists to understand the perspective of the context in a better way. This review will definitely offer the platform for researchers to strategically design diverse novel indole derivatives having different promising pharmacological activities with reduced toxicity and side effects." @default.
- W2947657280 created "2019-06-07" @default.
- W2947657280 creator A5009077918 @default.
- W2947657280 creator A5061757758 @default.
- W2947657280 date "2019-08-01" @default.
- W2947657280 modified "2023-10-11" @default.
- W2947657280 title "Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives" @default.
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