Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947663669> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2947663669 abstract "Aim: We aimed to investigate IL-33 polymorphisms with risk of colorectal cancer (CRC). Materials & methods: IL-33 rs7025417 and rs1332290 were genotyped using a quantitative allelic Taqman assay. The expression of IL-33 mRNA was determined by real-time PCR and promoter activity was assayed using the Dual-Luciferase Reporter Assay. Results: The IL-33 rs7025417 CC genotype and C allele may decrease CRC risk. The IL-33 rs1332290 AC carriers had an increased risk of developing clinical Stage III–IV CRC. Lower levels of IL-33 mRNA were present in individuals with the rs7025417 CC genotype. Moreover, the rs7025417 C allele suppressed promoter activity of IL-33. Conclusion: These data suggest that the rs7025417 CC genotype may downregulate IL-33 mRNA and subsequently reduce the risk of CRC." @default.
- W2947663669 created "2019-06-07" @default.
- W2947663669 creator A5012788229 @default.
- W2947663669 creator A5036291399 @default.
- W2947663669 creator A5071699711 @default.
- W2947663669 date "2019-05-01" @default.
- W2947663669 modified "2023-09-23" @default.
- W2947663669 title "A functional polymorphism in the promoter region of IL-33 is associated with the reduced risk of colorectal cancer" @default.
- W2947663669 cites W1519737652 @default.
- W2947663669 cites W1793113882 @default.
- W2947663669 cites W1968955229 @default.
- W2947663669 cites W2004066105 @default.
- W2947663669 cites W2031194689 @default.
- W2947663669 cites W2036675396 @default.
- W2947663669 cites W2043099698 @default.
- W2947663669 cites W2069249077 @default.
- W2947663669 cites W2093396768 @default.
- W2947663669 cites W2097733438 @default.
- W2947663669 cites W2097745561 @default.
- W2947663669 cites W2110115488 @default.
- W2947663669 cites W2112666212 @default.
- W2947663669 cites W2117726975 @default.
- W2947663669 cites W2130615734 @default.
- W2947663669 cites W2144563711 @default.
- W2947663669 cites W2148304468 @default.
- W2947663669 cites W2148925188 @default.
- W2947663669 cites W2156432160 @default.
- W2947663669 cites W2157885410 @default.
- W2947663669 cites W2168272873 @default.
- W2947663669 cites W2283478476 @default.
- W2947663669 cites W2372899587 @default.
- W2947663669 cites W2772638559 @default.
- W2947663669 cites W2782902998 @default.
- W2947663669 cites W2795176771 @default.
- W2947663669 cites W906314213 @default.
- W2947663669 doi "https://doi.org/10.2217/bmm-2018-0249" @default.
- W2947663669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31140826" @default.
- W2947663669 hasPublicationYear "2019" @default.
- W2947663669 type Work @default.
- W2947663669 sameAs 2947663669 @default.
- W2947663669 citedByCount "2" @default.
- W2947663669 countsByYear W29476636692021 @default.
- W2947663669 countsByYear W29476636692022 @default.
- W2947663669 crossrefType "journal-article" @default.
- W2947663669 hasAuthorship W2947663669A5012788229 @default.
- W2947663669 hasAuthorship W2947663669A5036291399 @default.
- W2947663669 hasAuthorship W2947663669A5071699711 @default.
- W2947663669 hasConcept C101762097 @default.
- W2947663669 hasConcept C104317684 @default.
- W2947663669 hasConcept C121608353 @default.
- W2947663669 hasConcept C126322002 @default.
- W2947663669 hasConcept C135763542 @default.
- W2947663669 hasConcept C143660080 @default.
- W2947663669 hasConcept C143998085 @default.
- W2947663669 hasConcept C150194340 @default.
- W2947663669 hasConcept C153911025 @default.
- W2947663669 hasConcept C180754005 @default.
- W2947663669 hasConcept C48023723 @default.
- W2947663669 hasConcept C502942594 @default.
- W2947663669 hasConcept C526805850 @default.
- W2947663669 hasConcept C54355233 @default.
- W2947663669 hasConcept C71924100 @default.
- W2947663669 hasConcept C86803240 @default.
- W2947663669 hasConceptScore W2947663669C101762097 @default.
- W2947663669 hasConceptScore W2947663669C104317684 @default.
- W2947663669 hasConceptScore W2947663669C121608353 @default.
- W2947663669 hasConceptScore W2947663669C126322002 @default.
- W2947663669 hasConceptScore W2947663669C135763542 @default.
- W2947663669 hasConceptScore W2947663669C143660080 @default.
- W2947663669 hasConceptScore W2947663669C143998085 @default.
- W2947663669 hasConceptScore W2947663669C150194340 @default.
- W2947663669 hasConceptScore W2947663669C153911025 @default.
- W2947663669 hasConceptScore W2947663669C180754005 @default.
- W2947663669 hasConceptScore W2947663669C48023723 @default.
- W2947663669 hasConceptScore W2947663669C502942594 @default.
- W2947663669 hasConceptScore W2947663669C526805850 @default.
- W2947663669 hasConceptScore W2947663669C54355233 @default.
- W2947663669 hasConceptScore W2947663669C71924100 @default.
- W2947663669 hasConceptScore W2947663669C86803240 @default.
- W2947663669 hasLocation W29476636691 @default.
- W2947663669 hasLocation W29476636692 @default.
- W2947663669 hasOpenAccess W2947663669 @default.
- W2947663669 hasPrimaryLocation W29476636691 @default.
- W2947663669 hasRelatedWork W2007826257 @default.
- W2947663669 hasRelatedWork W2073144827 @default.
- W2947663669 hasRelatedWork W2094112220 @default.
- W2947663669 hasRelatedWork W2098531066 @default.
- W2947663669 hasRelatedWork W2142165702 @default.
- W2947663669 hasRelatedWork W2157811476 @default.
- W2947663669 hasRelatedWork W2348076134 @default.
- W2947663669 hasRelatedWork W2394279956 @default.
- W2947663669 hasRelatedWork W2404346623 @default.
- W2947663669 hasRelatedWork W2982265941 @default.
- W2947663669 isParatext "false" @default.
- W2947663669 isRetracted "false" @default.
- W2947663669 magId "2947663669" @default.
- W2947663669 workType "article" @default.