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• W2947679587 endingPage "134313" @default.
• W2947679587 startingPage "134313" @default.
• W2947679587 abstract "To explore the related factors of impulse control disorders (ICDs) in patients with Parkinson's disease (PD). We conducted a comprehensive search to identify studies on impulse control disorders in patients with Parkinson's disease. The related factors were compared to discriminate between PD patients with ICDs (PD-ICDs+)and PD patients without ICDs(PD-ICDs-)by a meta-analysis. 96 full-texts were assessed, and 15 were included (PD-ICDs+: 999; PD-ICDs-: 3507). The results showed that PD-ICDs + were significantly associated with younger age (SMD =-0.39, 95% CI: −0.50 – −0.28, P < 0.01), male sex(OR = 1.64, 95% CI: 1.34–2.02, P < 0.01), smoking habit(OR = 2.28, 95% CI: 1.16–4.47,P = 0.02), dopamine receptor agonist use(DA use) (OR = 3.41, 95% CI: 1.86–6.26,P < 0.01), dopamine receptor agonist equivalent daily dose(DA LEDD) (SMD = 0.42, 95% CI: 0.14 – 0.70,P = 0.003), levodopa equivalent daily dose(total LEDD) (SMD = 0.32, 95% CI: 0.14 – 0.49,P < 0.01), and amantadine use(OR = 2.26, 95% CI: 1.67–3.06,P < 0.01). While levodopa dose (SMD = 0.05, 95% CI: −0.09 –0.19,P = 0.48), Hoehn and Yahr stage(H & Y stage) (SMD =-0.05, 95% CI: −0.14 – 0.04,P = 0.27), MDS-UPDRS Part III score(UPDRS III score) (SMD =−0.05, 95% CI: −0.13 – 0.03,P = 0.24), PD duration (SMD =−0.23, 95% CI: 0.10 – 0.37,P < 0.01)and Mini-Mental Status Examination score (MMSE score) (SMD = 0.10, 95% CI: −0.11 – 0.31,P = 0.33)were not related with PD-ICDs+. Our study confirmed the previous results that younger age, male gender, smoking habit, longer PD duration, DA use, DA LEDD, total LEDD were high risk factors of PD-ICDs+." @default.
• W2947679587 created "2019-06-07" @default.
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• W2947679587 date "2019-08-01" @default.
• W2947679587 modified "2023-09-23" @default.
• W2947679587 title "Meta-analysis of related factors of impulse control disorders in patients with Parkinson's disease" @default.
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• W2947679587 doi "https://doi.org/10.1016/j.neulet.2019.134313" @default.
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• W2947679587 hasPublicationYear "2019" @default.
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