FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947716066> ?p ?o ?g. }

• W2947716066 abstract "e15094 Background: Selection for surgery in patients with colorectal liver metastases (CRLM) remains poorly accurate. We evaluated if baseline metabolic characteristics of CRLM, as assessed by [18]-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography ( 18 FDG-PET/CT), may predict the postoperative outcome in patients operated for CRLM. Methods: In a series of 450 patients operated for CRLM, we retrospectively identified 2 groups: The long-term survival (LTS), as defined by postoperative recurrence-free survival (RFS)≥5 years, and the early relapse groups (ER), as defined by RFS < 1 year. Clinicopathologic characteristics, Clinical Risk Score (CRS) and baseline 18 FDG-PET/CT metabolic parameters were analyzed. Baseline 18 FDG-PET/CT was performed at the time of diagnosis of CRLM, before any preoperative treatment. Low and high-risk CRS were defined by scores of 0 to 2 and 3 to 5, respectively. Metabolic CRS (mCRS) was implemented, using 1 additional point to the standard CRS when the highest tumor standardized uptake value (SUV max ) and normal liver mean SUV (SUV mean(liver) ) ratio was > 4.3. Low and high-risk mCRS were defined by scores of 0 to 2 and 3 to 6, respectively. Results: We analyzed 53 patients. No difference was observed between LTS (n = 23) and ER (n = 30) groups for clinicopathologic parameters related to the primary tumor and CRLM, CRS and rates of low/high risk CRS. All metabolic parameters analyzed, including SUV max and SUV peak , at the exception of metabolic tumor volume, were significantly increased in ER group. Median SUV max /SUV mean(liver) ratio was significantly increased in the ER vs LTS, respectively of 4.2 and 2.8 (p = 0.008). mCRS was significantly higher in ER as compared to LTS patients (p = 0.024), while 61% of the LTS patients had a low-risk mCRS and 73% of the ER patients had a high-risk mCRS (p = 0.023). Conclusions: Baseline 18 FDG-PET/CT characteristics demonstrate an increased tumor glucose uptake in patients who rapidly recur after curative-intent surgery for CRLM. The introduction of these data into clinical risk model may represent a new tool to improve selection for surgery in patients with CRLM." @default.
• W2947716066 created "2019-06-07" @default.
• W2947716066 creator A5003065271 @default.
• W2947716066 creator A5017711430 @default.
• W2947716066 creator A5019230100 @default.
• W2947716066 creator A5023253691 @default.
• W2947716066 creator A5044350507 @default.
• W2947716066 creator A5045470802 @default.
• W2947716066 creator A5058433072 @default.
• W2947716066 creator A5060058983 @default.
• W2947716066 creator A5064221894 @default.
• W2947716066 creator A5075262723 @default.
• W2947716066 creator A5076399682 @default.
• W2947716066 creator A5081270901 @default.
• W2947716066 creator A5081897500 @default.
• W2947716066 date "2019-05-20" @default.
• W2947716066 modified "2023-09-24" @default.
• W2947716066 title "The metabolic clinical risk score (mCRS) as a new prognostic model for surgical decision in patients with colorectal liver metastases." @default.
• W2947716066 doi "https://doi.org/10.1200/jco.2019.37.15_suppl.e15094" @default.
• W2947716066 hasPublicationYear "2019" @default.
• W2947716066 type Work @default.
• W2947716066 sameAs 2947716066 @default.
• W2947716066 citedByCount "0" @default.
• W2947716066 crossrefType "journal-article" @default.
• W2947716066 hasAuthorship W2947716066A5003065271 @default.
• W2947716066 hasAuthorship W2947716066A5017711430 @default.
• W2947716066 hasAuthorship W2947716066A5019230100 @default.
• W2947716066 hasAuthorship W2947716066A5023253691 @default.
• W2947716066 hasAuthorship W2947716066A5044350507 @default.
• W2947716066 hasAuthorship W2947716066A5045470802 @default.
• W2947716066 hasAuthorship W2947716066A5058433072 @default.
• W2947716066 hasAuthorship W2947716066A5060058983 @default.
• W2947716066 hasAuthorship W2947716066A5064221894 @default.
• W2947716066 hasAuthorship W2947716066A5075262723 @default.
• W2947716066 hasAuthorship W2947716066A5076399682 @default.
• W2947716066 hasAuthorship W2947716066A5081270901 @default.
• W2947716066 hasAuthorship W2947716066A5081897500 @default.
• W2947716066 hasConcept C121608353 @default.
• W2947716066 hasConcept C126322002 @default.
• W2947716066 hasConcept C141071460 @default.
• W2947716066 hasConcept C143998085 @default.
• W2947716066 hasConcept C159110652 @default.
• W2947716066 hasConcept C2776909242 @default.
• W2947716066 hasConcept C526805850 @default.
• W2947716066 hasConcept C71924100 @default.
• W2947716066 hasConceptScore W2947716066C121608353 @default.
• W2947716066 hasConceptScore W2947716066C126322002 @default.
• W2947716066 hasConceptScore W2947716066C141071460 @default.
• W2947716066 hasConceptScore W2947716066C143998085 @default.
• W2947716066 hasConceptScore W2947716066C159110652 @default.
• W2947716066 hasConceptScore W2947716066C2776909242 @default.
• W2947716066 hasConceptScore W2947716066C526805850 @default.
• W2947716066 hasConceptScore W2947716066C71924100 @default.
• W2947716066 hasLocation W29477160661 @default.
• W2947716066 hasOpenAccess W2947716066 @default.
• W2947716066 hasPrimaryLocation W29477160661 @default.
• W2947716066 hasRelatedWork W1765193236 @default.
• W2947716066 hasRelatedWork W2007849159 @default.
• W2947716066 hasRelatedWork W2047890553 @default.
• W2947716066 hasRelatedWork W2069060517 @default.
• W2947716066 hasRelatedWork W2138457185 @default.
• W2947716066 hasRelatedWork W2148354282 @default.
• W2947716066 hasRelatedWork W2343539449 @default.
• W2947716066 hasRelatedWork W2600482326 @default.
• W2947716066 hasRelatedWork W2885687532 @default.
• W2947716066 hasRelatedWork W2965150666 @default.
• W2947716066 hasRelatedWork W2969612538 @default.
• W2947716066 hasRelatedWork W2998733644 @default.
• W2947716066 hasRelatedWork W3030038086 @default.
• W2947716066 hasRelatedWork W3030234777 @default.
• W2947716066 hasRelatedWork W3092358127 @default.
• W2947716066 hasRelatedWork W3121282688 @default.
• W2947716066 hasRelatedWork W3177231829 @default.
• W2947716066 hasRelatedWork W3192763781 @default.
• W2947716066 hasRelatedWork W3203516984 @default.
• W2947716066 hasRelatedWork W3209718855 @default.
• W2947716066 isParatext "false" @default.
• W2947716066 isRetracted "false" @default.
• W2947716066 magId "2947716066" @default.
• W2947716066 workType "article" @default.