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• W2947750886 abstract "Six novel monacolin analogs, monacolins V1-V6 (1-6), together with seven known ones (7-13), were isolated from the ethyl acetate extract of red yeast rice. Their structures and absolute configurations were determined by spectroscopic methods, especially 2D NMR (1H-1HCOSY, HSQC, HMBC, and NOESY/ROESY) and CD spectroscopic analyses as well as chemical derivation. Monacolins V2 (2) and V3 (3) represent the first examples of monacolins with 3-hydroxybutyrate substitute. The anti-inflammatory inhibitory activities against the lipopolysaccharide (LPS) induced NO production in BV-2 cells as well as antioxidant activities against rat liver microsomal lipid peroxidation were evaluated." @default.
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• W2947750886 date "2019-05-01" @default.
• W2947750886 modified "2023-10-17" @default.
• W2947750886 title "Six new monacolin analogs from red yeast rice" @default.
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• W2947750886 doi "https://doi.org/10.1016/s1875-5364(19)30046-9" @default.
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