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• W2947756905 abstract "The rapid development of immuno-oncology (I-O) therapies for multiple types of cancer has transformed the cancer treatment landscape and brightened the long-term outlook for many patients with advanced cancer. Responding to ongoing efforts to generate value assessments for novel therapies, multiple stakeholders have been considering the question of What makes I-O transformative? Evaluating the distinct features and attributes of these therapies, and better characterizing how patients experience them, will inform such assessments. This paper defines ways in which treatment with I-O is different from other therapies. It also proposes key aspects and attributes of I-O therapies that should be considered in any assessment of their value and seeks to address evidence gaps in existing value frameworks given the unique properties of patient outcomes with I-O therapy. The paper concludes with a data needs catalogue (DNC) predicated on the belief that multiple key, unique elements that are necessary to fully characterize the value of I-O therapies are not routinely or robustly measured in current clinical practice or reimbursement databases and are infrequently captured in existing research studies. A better characterization of the benefit of I-O treatment will allow a more thorough assessment of its benefits and provide a template for the design and prioritization of future clinical trials and a roadmap for healthcare insurers to optimize coverage for patients with cancers eligible for I-O therapy." @default.
• W2947756905 created "2019-06-07" @default.
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• W2947756905 date "2019-05-17" @default.
• W2947756905 modified "2023-10-15" @default.
• W2947756905 title "The promise of Immuno-oncology: implications for defining the value of cancer treatment" @default.
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• W2947756905 doi "https://doi.org/10.1186/s40425-019-0594-0" @default.
• W2947756905 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6525438" @default.
• W2947756905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31101066" @default.
• W2947756905 hasPublicationYear "2019" @default.
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