Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947758753> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2947758753 abstract "Purpose: This study aimed to construct a calibration curve for high-dose exposure using cell fusion-induced premature chromosome condensation (PCC). Some of the associated practicalities and methodological details were also investigated. Materials and methods: Peripheral blood from two donors was used. PCC mediated by fusing mitotic CHO cells with interphase lymphocytes was carried out. Lymphocytes were irradiated with 60Co (0-20 Gy) and held at 37 °C for 24 h post exposure. Results: The protocol for PCC induction was effective at all doses and the number of rings increased with increasing dose. No significant difference was found between the donors (p = .896) and data were pooled. Ring aberration frequencies followed a Poisson distribution and the dose-response relationship favored a linear fitting: Y = 0.0007(±0.0004)+0.0186(±0.001)×D. Blind tests showed that the estimated doses were all within the 95% confidence limits of the delivered doses. This study has shown that it is valid to score only 100 cells per sample in a triage mode for doses above 5 Gy and that it is valid to score only hollow rings to reduce the scoring time. Conclusion: Scoring rings in cell fusion-induced PCC assay can be a feasible and fast approach for the analysis of high-dose exposures." @default.
- W2947758753 created "2019-06-07" @default.
- W2947758753 creator A5001325663 @default.
- W2947758753 creator A5002006217 @default.
- W2947758753 creator A5041686111 @default.
- W2947758753 creator A5048266777 @default.
- W2947758753 creator A5086765866 @default.
- W2947758753 date "2019-06-12" @default.
- W2947758753 modified "2023-10-18" @default.
- W2947758753 title "Scoring rings in the cell fusion-induced premature chromosome condensation (PCC) assay for high dose radiation exposure estimation after gamma-ray exposure" @default.
- W2947758753 cites W104662766 @default.
- W2947758753 cites W1967936039 @default.
- W2947758753 cites W1976051383 @default.
- W2947758753 cites W1980803465 @default.
- W2947758753 cites W1990035697 @default.
- W2947758753 cites W1990399725 @default.
- W2947758753 cites W1999663423 @default.
- W2947758753 cites W2038508955 @default.
- W2947758753 cites W2046106996 @default.
- W2947758753 cites W2070284675 @default.
- W2947758753 cites W2071177028 @default.
- W2947758753 cites W2094543672 @default.
- W2947758753 cites W2103486381 @default.
- W2947758753 cites W2109885006 @default.
- W2947758753 cites W2117569538 @default.
- W2947758753 cites W2132281936 @default.
- W2947758753 cites W2137511483 @default.
- W2947758753 cites W2144554917 @default.
- W2947758753 cites W2152240847 @default.
- W2947758753 cites W2484098330 @default.
- W2947758753 cites W2493435327 @default.
- W2947758753 cites W2515648387 @default.
- W2947758753 cites W2527862642 @default.
- W2947758753 cites W2909520436 @default.
- W2947758753 doi "https://doi.org/10.1080/09553002.2019.1625465" @default.
- W2947758753 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31140905" @default.
- W2947758753 hasPublicationYear "2019" @default.
- W2947758753 type Work @default.
- W2947758753 sameAs 2947758753 @default.
- W2947758753 citedByCount "6" @default.
- W2947758753 countsByYear W29477587532020 @default.
- W2947758753 countsByYear W29477587532021 @default.
- W2947758753 countsByYear W29477587532022 @default.
- W2947758753 crossrefType "journal-article" @default.
- W2947758753 hasAuthorship W2947758753A5001325663 @default.
- W2947758753 hasAuthorship W2947758753A5002006217 @default.
- W2947758753 hasAuthorship W2947758753A5041686111 @default.
- W2947758753 hasAuthorship W2947758753A5048266777 @default.
- W2947758753 hasAuthorship W2947758753A5086765866 @default.
- W2947758753 hasConcept C104317684 @default.
- W2947758753 hasConcept C1491633281 @default.
- W2947758753 hasConcept C16685009 @default.
- W2947758753 hasConcept C178108356 @default.
- W2947758753 hasConcept C2781034694 @default.
- W2947758753 hasConcept C29537977 @default.
- W2947758753 hasConcept C2989005 @default.
- W2947758753 hasConcept C30481170 @default.
- W2947758753 hasConcept C53226629 @default.
- W2947758753 hasConcept C54355233 @default.
- W2947758753 hasConcept C71924100 @default.
- W2947758753 hasConcept C79410662 @default.
- W2947758753 hasConcept C86803240 @default.
- W2947758753 hasConcept C93304396 @default.
- W2947758753 hasConcept C98274493 @default.
- W2947758753 hasConceptScore W2947758753C104317684 @default.
- W2947758753 hasConceptScore W2947758753C1491633281 @default.
- W2947758753 hasConceptScore W2947758753C16685009 @default.
- W2947758753 hasConceptScore W2947758753C178108356 @default.
- W2947758753 hasConceptScore W2947758753C2781034694 @default.
- W2947758753 hasConceptScore W2947758753C29537977 @default.
- W2947758753 hasConceptScore W2947758753C2989005 @default.
- W2947758753 hasConceptScore W2947758753C30481170 @default.
- W2947758753 hasConceptScore W2947758753C53226629 @default.
- W2947758753 hasConceptScore W2947758753C54355233 @default.
- W2947758753 hasConceptScore W2947758753C71924100 @default.
- W2947758753 hasConceptScore W2947758753C79410662 @default.
- W2947758753 hasConceptScore W2947758753C86803240 @default.
- W2947758753 hasConceptScore W2947758753C93304396 @default.
- W2947758753 hasConceptScore W2947758753C98274493 @default.
- W2947758753 hasLocation W29477587531 @default.
- W2947758753 hasLocation W29477587532 @default.
- W2947758753 hasOpenAccess W2947758753 @default.
- W2947758753 hasPrimaryLocation W29477587531 @default.
- W2947758753 hasRelatedWork W1980169844 @default.
- W2947758753 hasRelatedWork W1991790766 @default.
- W2947758753 hasRelatedWork W2014271394 @default.
- W2947758753 hasRelatedWork W2064738349 @default.
- W2947758753 hasRelatedWork W2068072725 @default.
- W2947758753 hasRelatedWork W2133076042 @default.
- W2947758753 hasRelatedWork W2171319481 @default.
- W2947758753 hasRelatedWork W2213639261 @default.
- W2947758753 hasRelatedWork W3030137584 @default.
- W2947758753 hasRelatedWork W2155577502 @default.
- W2947758753 isParatext "false" @default.
- W2947758753 isRetracted "false" @default.
- W2947758753 magId "2947758753" @default.
- W2947758753 workType "article" @default.