Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947900703> ?p ?o ?g. }
- W2947900703 abstract "We study the role of a biomimetic actin network during the application of electric pulses that induce electroporation or electropermeabilization, using giant unilamellar vesicles (GUVs) as a model system. The actin cortex, a subjacently attached interconnected network of actin filaments, regulates the shape and mechanical properties of the plasma membrane of mammalian cells, and is a major factor influencing the mechanical response of the cell to external physical cues. We demonstrate that the presence of an actin shell inhibits the formation of macropores in the electroporated GUVs. Additionally, experiments on the uptake of dye molecules after electroporation show that the actin network slows down the resealing process of the permeabilized membrane. We further analyze the stability of the actin network inside the GUVs exposed to high electric pulses. We find disruption of the actin layer that is likely due to the electrophoretic forces acting on the actin filaments during the permeabilization of the GUVs. Our findings on the GUVs containing a biomimetic network provide a step towards understanding the discrepancies between the electroporation mechanism of a living cell and its simplified model of the empty GUV." @default.
- W2947900703 created "2019-06-07" @default.
- W2947900703 creator A5007938391 @default.
- W2947900703 creator A5017521735 @default.
- W2947900703 creator A5046993858 @default.
- W2947900703 creator A5051080215 @default.
- W2947900703 creator A5057206178 @default.
- W2947900703 creator A5063880539 @default.
- W2947900703 creator A5081100121 @default.
- W2947900703 creator A5082014248 @default.
- W2947900703 creator A5083550174 @default.
- W2947900703 creator A5086123786 @default.
- W2947900703 date "2019-05-31" @default.
- W2947900703 modified "2023-10-13" @default.
- W2947900703 title "Response of an actin network in vesicles under electric pulses" @default.
- W2947900703 cites W107513903 @default.
- W2947900703 cites W1915038288 @default.
- W2947900703 cites W1925986828 @default.
- W2947900703 cites W1963695337 @default.
- W2947900703 cites W1969959009 @default.
- W2947900703 cites W1970151194 @default.
- W2947900703 cites W1971244095 @default.
- W2947900703 cites W1972647868 @default.
- W2947900703 cites W1972740202 @default.
- W2947900703 cites W1973142530 @default.
- W2947900703 cites W1977926556 @default.
- W2947900703 cites W1986790570 @default.
- W2947900703 cites W1994582298 @default.
- W2947900703 cites W1995950964 @default.
- W2947900703 cites W1997048292 @default.
- W2947900703 cites W1998287390 @default.
- W2947900703 cites W2002240779 @default.
- W2947900703 cites W2004041935 @default.
- W2947900703 cites W2008800998 @default.
- W2947900703 cites W2010601263 @default.
- W2947900703 cites W2014222168 @default.
- W2947900703 cites W2022001508 @default.
- W2947900703 cites W2027286341 @default.
- W2947900703 cites W2030409341 @default.
- W2947900703 cites W2037219383 @default.
- W2947900703 cites W2037882355 @default.
- W2947900703 cites W2047474055 @default.
- W2947900703 cites W2049346145 @default.
- W2947900703 cites W2052639082 @default.
- W2947900703 cites W2063301038 @default.
- W2947900703 cites W2068438163 @default.
- W2947900703 cites W2071624468 @default.
- W2947900703 cites W2071747332 @default.
- W2947900703 cites W2072303718 @default.
- W2947900703 cites W2080484884 @default.
- W2947900703 cites W2084812227 @default.
- W2947900703 cites W2089005990 @default.
- W2947900703 cites W2091442346 @default.
- W2947900703 cites W2091443281 @default.
- W2947900703 cites W2092575669 @default.
- W2947900703 cites W2092648157 @default.
- W2947900703 cites W2098692651 @default.
- W2947900703 cites W2099040624 @default.
- W2947900703 cites W2102395953 @default.
- W2947900703 cites W2103133044 @default.
- W2947900703 cites W2119823031 @default.
- W2947900703 cites W2121381406 @default.
- W2947900703 cites W2129185438 @default.
- W2947900703 cites W2146676040 @default.
- W2947900703 cites W2155161956 @default.
- W2947900703 cites W2155703402 @default.
- W2947900703 cites W2156090333 @default.
- W2947900703 cites W2161887308 @default.
- W2947900703 cites W2162876871 @default.
- W2947900703 cites W2166973079 @default.
- W2947900703 cites W2215612510 @default.
- W2947900703 cites W2287211265 @default.
- W2947900703 cites W2319910816 @default.
- W2947900703 cites W2342739775 @default.
- W2947900703 cites W2552861607 @default.
- W2947900703 cites W2616664670 @default.
- W2947900703 cites W2805128070 @default.
- W2947900703 cites W3098250479 @default.
- W2947900703 cites W4213068678 @default.
- W2947900703 cites W4255642433 @default.
- W2947900703 doi "https://doi.org/10.1038/s41598-019-44613-5" @default.
- W2947900703 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6544639" @default.
- W2947900703 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31148577" @default.
- W2947900703 hasPublicationYear "2019" @default.
- W2947900703 type Work @default.
- W2947900703 sameAs 2947900703 @default.
- W2947900703 citedByCount "40" @default.
- W2947900703 countsByYear W29479007032019 @default.
- W2947900703 countsByYear W29479007032020 @default.
- W2947900703 countsByYear W29479007032021 @default.
- W2947900703 countsByYear W29479007032022 @default.
- W2947900703 countsByYear W29479007032023 @default.
- W2947900703 crossrefType "journal-article" @default.
- W2947900703 hasAuthorship W2947900703A5007938391 @default.
- W2947900703 hasAuthorship W2947900703A5017521735 @default.
- W2947900703 hasAuthorship W2947900703A5046993858 @default.
- W2947900703 hasAuthorship W2947900703A5051080215 @default.
- W2947900703 hasAuthorship W2947900703A5057206178 @default.
- W2947900703 hasAuthorship W2947900703A5063880539 @default.
- W2947900703 hasAuthorship W2947900703A5081100121 @default.