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- W2947919732 endingPage "1239" @default.
- W2947919732 startingPage "1239" @default.
- W2947919732 abstract "Patients frequently wonder whether their dietary pattern influences the course of inflammatory bowel disease (IBD). Many patients even avoid certain foods that aggravate their symptoms. Although interest in nutritional interventions is rising among physicians, the current application of nutritional interventions in the IBD population is limited due to the lack of scientific evidence from clinical trials. Several studies, however, have identified associations between diet, gut microbiota, intestinal epithelial integrity, and mucosal immune responses. In patients consuming predominantly a Western diet high in n-6 poly-unsaturated fatty acids (PUFAs), sugars, and meat, and low in fruits and vegetables, an impaired gut epithelial barrier and disturbances in the intestinal microbiota have been observed, resulting in a chronic mucosal inflammation. An anti-inflammatory diet may restore this disbalance. In this review, we discuss the effects of diet on the composition of the microbiota, the gut epithelial barrier function, and the mucosal immune system." @default.
- W2947919732 created "2019-06-07" @default.
- W2947919732 creator A5019612457 @default.
- W2947919732 creator A5064593420 @default.
- W2947919732 creator A5089553422 @default.
- W2947919732 date "2019-05-31" @default.
- W2947919732 modified "2023-10-15" @default.
- W2947919732 title "Towards a Food Pharmacy: Immunologic Modulation through Diet" @default.
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- W2947919732 doi "https://doi.org/10.3390/nu11061239" @default.
- W2947919732 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6627620" @default.
- W2947919732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31159179" @default.
- W2947919732 hasPublicationYear "2019" @default.
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