FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947954101> ?p ?o ?g. }

• W2947954101 endingPage "1602" @default.
• W2947954101 startingPage "1595" @default.
• W2947954101 abstract "Long noncoding RNA, long intergenic non-protein-coding RNA p53-induced transcript (LINC-PINT) was showed to be involved in cancer development. However, the biological effect of LINC-PINT on non-small cell lung cancer (NSCLC) remains unknown. Here, we aimed to investigate the role and underlying mechanism of LINC-PINT in NSCLC. Quantitative real-time polymerase chain reaction (qRT-PCR) was used to measure the level of LINC-PINT in NSCLC tissues and cell lines. Cell counting kit-8 (CCK-8), flow cytometry, migration and transwell invasion assays were used to investigate cell proliferation, cell cycle, cell migration and invasion, respectively. The targets of LINC-PINT were verified by both luciferase reporter assay and RNA immunoprecipitation assay. Tumour xenografts were used to reveal the effect of LINC-PINT on tumourigenesis in vivo. We observed that LINC-PINT expression increased in both NSCLC tissues and cell lines. Function assays exhibited that LINC-PINT reduced NSCLC cell proliferation, cell cycle, cell migration and invasion in vitro. We also indicated that LINC-PINT mediated inhibitory effect on cell proliferation, cell cycle, cell migration and invasion by miR-208a-3p/programmed cell death 4 (PDCD4) in NSCLC cells. These findings indicated that LINC-PINT functions as a tumour-suppressor that exerts important regulatory roles in NSCLC progression by sponging miR-208a-3p/PDCD4." @default.
• W2947954101 created "2019-06-07" @default.
• W2947954101 creator A5015956284 @default.
• W2947954101 creator A5020048658 @default.
• W2947954101 creator A5072362581 @default.
• W2947954101 creator A5079320328 @default.
• W2947954101 creator A5088027886 @default.
• W2947954101 creator A5088640614 @default.
• W2947954101 date "2019-04-23" @default.
• W2947954101 modified "2023-09-26" @default.
• W2947954101 title "Long noncoding RNA LINC-PINT inhibits non-small cell lung cancer progression through sponging miR-218-5p/PDCD4" @default.
• W2947954101 cites W1516764883 @default.
• W2947954101 cites W2154395350 @default.
• W2947954101 cites W2524970130 @default.
• W2947954101 cites W2563848751 @default.
• W2947954101 cites W2735239806 @default.
• W2947954101 cites W2750745381 @default.
• W2947954101 cites W2768610432 @default.
• W2947954101 cites W2784570320 @default.
• W2947954101 cites W2791458703 @default.
• W2947954101 cites W2800428052 @default.
• W2947954101 cites W2802438317 @default.
• W2947954101 cites W2808862148 @default.
• W2947954101 cites W2811073748 @default.
• W2947954101 cites W2811185887 @default.
• W2947954101 cites W2883909272 @default.
• W2947954101 cites W2887381926 @default.
• W2947954101 cites W2887554293 @default.
• W2947954101 cites W2887797268 @default.
• W2947954101 cites W2889362839 @default.
• W2947954101 cites W2891953132 @default.
• W2947954101 cites W2897137698 @default.
• W2947954101 cites W2897443184 @default.
• W2947954101 cites W2899821098 @default.
• W2947954101 cites W2905350107 @default.
• W2947954101 cites W3141910095 @default.
• W2947954101 doi "https://doi.org/10.1080/21691401.2019.1605371" @default.
• W2947954101 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31010333" @default.
• W2947954101 hasPublicationYear "2019" @default.
• W2947954101 type Work @default.
• W2947954101 sameAs 2947954101 @default.
• W2947954101 citedByCount "29" @default.
• W2947954101 countsByYear W29479541012019 @default.
• W2947954101 countsByYear W29479541012020 @default.
• W2947954101 countsByYear W29479541012021 @default.
• W2947954101 countsByYear W29479541012022 @default.
• W2947954101 countsByYear W29479541012023 @default.
• W2947954101 crossrefType "journal-article" @default.
• W2947954101 hasAuthorship W2947954101A5015956284 @default.
• W2947954101 hasAuthorship W2947954101A5020048658 @default.
• W2947954101 hasAuthorship W2947954101A5072362581 @default.
• W2947954101 hasAuthorship W2947954101A5079320328 @default.
• W2947954101 hasAuthorship W2947954101A5088027886 @default.
• W2947954101 hasAuthorship W2947954101A5088640614 @default.
• W2947954101 hasBestOaLocation W29479541011 @default.
• W2947954101 hasConcept C104317684 @default.
• W2947954101 hasConcept C143998085 @default.
• W2947954101 hasConcept C1491633281 @default.
• W2947954101 hasConcept C153911025 @default.
• W2947954101 hasConcept C2776256026 @default.
• W2947954101 hasConcept C29537977 @default.
• W2947954101 hasConcept C502942594 @default.
• W2947954101 hasConcept C54355233 @default.
• W2947954101 hasConcept C553184892 @default.
• W2947954101 hasConcept C62112901 @default.
• W2947954101 hasConcept C62203573 @default.
• W2947954101 hasConcept C67705224 @default.
• W2947954101 hasConcept C71924100 @default.
• W2947954101 hasConcept C81885089 @default.
• W2947954101 hasConcept C86803240 @default.
• W2947954101 hasConcept C95444343 @default.
• W2947954101 hasConceptScore W2947954101C104317684 @default.
• W2947954101 hasConceptScore W2947954101C143998085 @default.
• W2947954101 hasConceptScore W2947954101C1491633281 @default.
• W2947954101 hasConceptScore W2947954101C153911025 @default.
• W2947954101 hasConceptScore W2947954101C2776256026 @default.
• W2947954101 hasConceptScore W2947954101C29537977 @default.
• W2947954101 hasConceptScore W2947954101C502942594 @default.
• W2947954101 hasConceptScore W2947954101C54355233 @default.
• W2947954101 hasConceptScore W2947954101C553184892 @default.
• W2947954101 hasConceptScore W2947954101C62112901 @default.
• W2947954101 hasConceptScore W2947954101C62203573 @default.
• W2947954101 hasConceptScore W2947954101C67705224 @default.
• W2947954101 hasConceptScore W2947954101C71924100 @default.
• W2947954101 hasConceptScore W2947954101C81885089 @default.
• W2947954101 hasConceptScore W2947954101C86803240 @default.
• W2947954101 hasConceptScore W2947954101C95444343 @default.
• W2947954101 hasIssue "1" @default.
• W2947954101 hasLocation W29479541011 @default.
• W2947954101 hasLocation W29479541012 @default.
• W2947954101 hasLocation W29479541013 @default.
• W2947954101 hasOpenAccess W2947954101 @default.
• W2947954101 hasPrimaryLocation W29479541011 @default.
• W2947954101 hasRelatedWork W2350231700 @default.
• W2947954101 hasRelatedWork W2355897695 @default.
• W2947954101 hasRelatedWork W2356093969 @default.
• W2947954101 hasRelatedWork W2356588131 @default.
• W2947954101 hasRelatedWork W2363589313 @default.

• next