Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947977952> ?p ?o ?g. }
- W2947977952 endingPage "8" @default.
- W2947977952 startingPage "1" @default.
- W2947977952 abstract "The aim of the study was to investigate the independent and combined effects of the cortisol-to-cortisone ratio (F/E) and 11-deoxycortisol on prediabetes and type 2 diabetes mellitus (T2DM) among different genders.A case-control study was performed including 2676 participants from the Henan Rural Cohort Study. Liquid chromatography-tandem mass spectrometry was used to assess serum cortisol, cortisone, and 11-deoxycortisol. Conditional logistic regression was performed to estimate the associations between hormones and outcomes.After adjusting for multiple variables, the negative associations of F/E and 11-dexyocortisol with T2DM were observed in females (T3 vs. T1: OR = 0.56, 95% CI: 0.39-0.80 for F/E; T3 vs. T1: OR = 0.44, 95% CI: 0.27-0.73 for 11-dexyocortisol). However, only 11-dexyocortisol showed a negative association with prediabetes both in males and females. Compared with the combination of low F/E and 11-dexyocortisol, the combination of middle F/E and high 11-dexyocortisol was significantly associated with prediabetes (OR = 0.29, 95% CI: 0.12-0.71) in males. Furthermore, the combination of high F/E and 11-dexyocortisol was associated with the lowest odds of prediabetes (OR = 0.39, 95% CI: 0.21-0.73) and T2DM (OR = 0.25, 95% CI: 0.12-0.52) in females.Serum F/E level was negatively associated with T2DM only in females whereas serum 11-deoxycortisol level was negatively associated with prediabetes in males and with prediabetes and T2DM in females. Additionally, their combination has a synergistic effect on T2DM." @default.
- W2947977952 created "2019-06-07" @default.
- W2947977952 creator A5000927257 @default.
- W2947977952 creator A5002354722 @default.
- W2947977952 creator A5014333694 @default.
- W2947977952 creator A5029466731 @default.
- W2947977952 creator A5033792942 @default.
- W2947977952 creator A5038214120 @default.
- W2947977952 creator A5050921210 @default.
- W2947977952 creator A5058990112 @default.
- W2947977952 creator A5061117894 @default.
- W2947977952 creator A5076154481 @default.
- W2947977952 creator A5078803635 @default.
- W2947977952 creator A5085922940 @default.
- W2947977952 creator A5089445095 @default.
- W2947977952 date "2019-06-02" @default.
- W2947977952 modified "2023-10-15" @default.
- W2947977952 title "Gender-Specific Independent and Combined Effects of the Cortisol-to-Cortisone Ratio and 11-Deoxycortisol on Prediabetes and Type 2 Diabetes Mellitus: From the Henan Rural Cohort Study" @default.
- W2947977952 cites W1889735098 @default.
- W2947977952 cites W1892205601 @default.
- W2947977952 cites W1989218081 @default.
- W2947977952 cites W1995377210 @default.
- W2947977952 cites W1997345544 @default.
- W2947977952 cites W1999517464 @default.
- W2947977952 cites W2004577393 @default.
- W2947977952 cites W2007585598 @default.
- W2947977952 cites W2011772722 @default.
- W2947977952 cites W2035183978 @default.
- W2947977952 cites W2036689296 @default.
- W2947977952 cites W2037148639 @default.
- W2947977952 cites W2046766433 @default.
- W2947977952 cites W2049915127 @default.
- W2947977952 cites W2066338366 @default.
- W2947977952 cites W2071180802 @default.
- W2947977952 cites W2078781462 @default.
- W2947977952 cites W2104442734 @default.
- W2947977952 cites W2113828398 @default.
- W2947977952 cites W2117057656 @default.
- W2947977952 cites W2117268230 @default.
- W2947977952 cites W2129221840 @default.
- W2947977952 cites W2137408083 @default.
- W2947977952 cites W2142594979 @default.
- W2947977952 cites W2143481659 @default.
- W2947977952 cites W2160305772 @default.
- W2947977952 cites W2162453805 @default.
- W2947977952 cites W2203608723 @default.
- W2947977952 cites W2263857782 @default.
- W2947977952 cites W2314021307 @default.
- W2947977952 cites W2328657113 @default.
- W2947977952 cites W2531432849 @default.
- W2947977952 cites W2590334872 @default.
- W2947977952 cites W2731349674 @default.
- W2947977952 cites W2794344612 @default.
- W2947977952 cites W2805850617 @default.
- W2947977952 cites W2913436703 @default.
- W2947977952 cites W41544179 @default.
- W2947977952 doi "https://doi.org/10.1155/2019/4693817" @default.
- W2947977952 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6589245" @default.
- W2947977952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31281850" @default.
- W2947977952 hasPublicationYear "2019" @default.
- W2947977952 type Work @default.
- W2947977952 sameAs 2947977952 @default.
- W2947977952 citedByCount "6" @default.
- W2947977952 countsByYear W29479779522020 @default.
- W2947977952 countsByYear W29479779522021 @default.
- W2947977952 countsByYear W29479779522023 @default.
- W2947977952 crossrefType "journal-article" @default.
- W2947977952 hasAuthorship W2947977952A5000927257 @default.
- W2947977952 hasAuthorship W2947977952A5002354722 @default.
- W2947977952 hasAuthorship W2947977952A5014333694 @default.
- W2947977952 hasAuthorship W2947977952A5029466731 @default.
- W2947977952 hasAuthorship W2947977952A5033792942 @default.
- W2947977952 hasAuthorship W2947977952A5038214120 @default.
- W2947977952 hasAuthorship W2947977952A5050921210 @default.
- W2947977952 hasAuthorship W2947977952A5058990112 @default.
- W2947977952 hasAuthorship W2947977952A5061117894 @default.
- W2947977952 hasAuthorship W2947977952A5076154481 @default.
- W2947977952 hasAuthorship W2947977952A5078803635 @default.
- W2947977952 hasAuthorship W2947977952A5085922940 @default.
- W2947977952 hasAuthorship W2947977952A5089445095 @default.
- W2947977952 hasBestOaLocation W29479779521 @default.
- W2947977952 hasConcept C126322002 @default.
- W2947977952 hasConcept C134018914 @default.
- W2947977952 hasConcept C151956035 @default.
- W2947977952 hasConcept C156957248 @default.
- W2947977952 hasConcept C2777180221 @default.
- W2947977952 hasConcept C2779668308 @default.
- W2947977952 hasConcept C2780484280 @default.
- W2947977952 hasConcept C2910068830 @default.
- W2947977952 hasConcept C555293320 @default.
- W2947977952 hasConcept C71924100 @default.
- W2947977952 hasConcept C72563966 @default.
- W2947977952 hasConceptScore W2947977952C126322002 @default.
- W2947977952 hasConceptScore W2947977952C134018914 @default.
- W2947977952 hasConceptScore W2947977952C151956035 @default.
- W2947977952 hasConceptScore W2947977952C156957248 @default.
- W2947977952 hasConceptScore W2947977952C2777180221 @default.
- W2947977952 hasConceptScore W2947977952C2779668308 @default.