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• W2947986570 abstract "Purpose Sodium MRI has shown promise for monitoring neoadjuvant chemotherapy response in breast cancer. The purpose of this work was to build a dual‐tuned bilateral proton/sodium breast coil for 7T MRI that provides sufficient SNR to enable sodium breast imaging in less than 10 minutes. Methods The proton/sodium coil consists of 2 shielded unilateral units: 1 for each breast. Each unit consists of 3 nested layers: (1) a 3‐loop solenoid for sodium excitation, (2) a 3‐loop solenoid for proton excitation and signal reception, and (3) a 4‐channel receive array for sodium signal reception. Benchmark measurements were performed in phantoms with and without the sodium receive array insert. In vivo images were acquired on a healthy volunteer. Results The sodium receive array boosted 1.5 to 3 times the SNR compared with the solenoid. Proton SNR loss due to residual interaction with the sodium array was less than 10%. The coil enabled sodium imaging in vivo with 2.8‐mm isotropic nominal resolution (~5‐mm real resolution) in 9:36 minutes. Conclusion The coil design that we propose addresses challenges associated with sodium's low SNR from a hardware perspective and offers the opportunity to investigate noninvasively breast tumor metabolism as a function of sodium concentration in patients undergoing neoadjuvant chemotherapy." @default.
• W2947986570 created "2019-06-07" @default.
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• W2947986570 date "2019-05-31" @default.
• W2947986570 modified "2023-10-16" @default.
• W2947986570 title "A dual‐tuned multichannel bilateral RF coil for ¹H/²³Na breast MRI at 7 T" @default.
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• W2947986570 doi "https://doi.org/10.1002/mrm.27829" @default.
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• W2947986570 hasPublicationYear "2019" @default.
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