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- W2948069430 abstract "### Key messages#### What is already known about this subject?#### What does this study add?#### How might this impact on clinical practice?Systemic lupus erythematosus (SLE) is a heterogenic connective tissue disease with a broad spectrum of clinical and laboratory manifestations. Due to this heterogeneity, SLE remains challenging to diagnose in clinical practice. In order to create a more homogeneous patient group, the American College of Rheumatology (ACR) developed classification criteria for research purposes in 1972.1 These criteria were revised in 1982 and 1997.2 3In 2012, the Systemic Lupus International Collaborating Clinics (SLICC) developed and validated new SLE classification criteria.4 The SLICC 2012 criteria performed better than the revised 1997 ACR criteria in terms of sensitivity (97% vs 83%), but were less specific (84% vs 96%).4Recently, new ACR–EULAR criteria have been proposed in order to improve specificity, while keeping the optimal sensitivity of the SLICC 2012 criteria. Several new elements were added, including the presence of antinuclear antibodies (ANA) as entry criterium, weighted scores for each criterium and domain scores.5–7 It is currently unknown how these criteria perform in patients with SLE with neuropsychiatric (NP) symptoms, one of the least understood manifestations of SLE.Therefore, we aimed to evaluate the performance of the proposed ACR–EULAR criteria in our cohort of patients with SLE presenting with NP symptoms.A retrospective cohort study was performed using electronic medical records of patients referred to the NPSLE clinic in the Leiden …" @default.
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- W2948069430 date "2019-06-01" @default.
- W2948069430 modified "2023-10-17" @default.
- W2948069430 title "Performance of the proposed ACR–EULAR classification criteria for systemic lupus erythematosus (SLE) in a cohort of patients with SLE with neuropsychiatric symptoms" @default.
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- W2948069430 doi "https://doi.org/10.1136/rmdopen-2019-000895" @default.
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