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- W2948234094 endingPage "172429" @default.
- W2948234094 startingPage "172429" @default.
- W2948234094 abstract "Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a frustrating syndrome. The pathogenesis and state of the art treatment of CP/CPPS are not known. A wide variety of therapies including anti-inflammatories, antibiotics, alpha-blockers, neuropathic pain modulators, and 5α-reductase inhibitors are in practice. These treatment strategies focus on alleviating symptoms in specific domains without treating root-cause and therapeutic outcome is far from satisfactory. We review the literature on current pharmacological treatments for CP/CPPS in detail and suggest future perspectives to modify the treatment strategies. We suggest that introducing novel treatment strategies such as gene editing, and Tregs expressing chimeric receptors may improve the treatment outcomes by inducing immune tolerance and controlling expression of pro-inflammatory cytokines." @default.
- W2948234094 created "2019-06-14" @default.
- W2948234094 creator A5005949567 @default.
- W2948234094 creator A5031035876 @default.
- W2948234094 creator A5057267443 @default.
- W2948234094 creator A5076042675 @default.
- W2948234094 creator A5079679275 @default.
- W2948234094 creator A5081935543 @default.
- W2948234094 creator A5082354680 @default.
- W2948234094 creator A5086628644 @default.
- W2948234094 date "2019-08-01" @default.
- W2948234094 modified "2023-09-25" @default.
- W2948234094 title "Interventions to chronic prostatitis/Chronic pelvic pain syndrome treatment. Where are we standing and what's next?" @default.
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