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• W2948360372 abstract "Drug-induced cholestasis represents a form of drug-induced liver disease that can lead to severe impairment of liver function. Numerous drugs have been shown to cause cholestasis and consequently bile duct toxicity. However, there is still lack of therapeutic tools that can prevent progression to advanced stages of liver injury. This review focuses on the various pathological mechanisms by which drugs express their hepatotoxic effects, as well as consequences of increased bile acid and toxin accumulation in the hepatocytes." @default.
• W2948360372 created "2019-06-14" @default.
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• W2948360372 date "2019-03-25" @default.
• W2948360372 modified "2023-09-25" @default.
• W2948360372 title "Mechanisms of Hepatic Cholestatic Drug Injury" @default.
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• W2948360372 doi "https://doi.org/10.14218/jcth.2018.00042" @default.
• W2948360372 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6441637" @default.
• W2948360372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30944824" @default.
• W2948360372 hasPublicationYear "2019" @default.
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