Matches in SemOpenAlex for { <https://semopenalex.org/work/W2948442936> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2948442936 endingPage "OR" @default.
- W2948442936 startingPage "283" @default.
- W2948442936 abstract "Aims: The aim of this work is to provide in depth characterization of patients with type 2 diabetes (T2D) with severe hypoglycemia and assess the role of structured nurse-led intervention on clinical outcome. Methods: Individuals with T2D and severe hypoglycemia requiring ambulance services assistance were recruited into the study. Participants were randomized into standard arm (n=64), managed using existing pathways, or intervention arm (n=60), receiving nurse-led support for a period of 90 days. A third group did not wish to participate in the interventional study but consented for their data to be collected and were analyzed separately (observational arm; n=36). Results: Of the 160 participants, 88 were men and median age was 77.0 (IQR 69.3-82.0) years. Mean HbA1c±SD was 59.7±16.1 mmol/mol and capillary glucose levels at ambulance crew arrival was 2.2±0.75 mmol/L. HbA1c, smoking status, age and presenting glucose were similar in the standard and intervention arms. 9 participants withdrew or lost to follow-up and were excluded from analysis. Individuals were followed-up for a median of 1350 days (IQR 870-1627) and mortality occurred in 67 participants (44.4%), with cardiovascular events as the leading cause (34%) followed by infections (27%). The number of deaths in the intervention arm was 17 (32%) compared with 31 (50%) in conventionally managed individuals (p=0.047), mainly due to a reduction in cardiovascular mortality [1 (2%) and 11 (18%), respectively; p Discussion: This pilot study demonstrates that cardiovascular events and infections are the main cause of mortality following severe hypoglycemia in the community requiring ambulance services assistance. A structured nurse-led intervention for 3 months reduces mortality primarily due to a decrease in cardiovascular events. Disclosure S. Pearson: Speaker9s Bureau; Self; Novo Nordisk Inc. K. Kulavarasalingam: None. P. Baxter: None. A.K. Mitchell-Gears: Other Relationship; Self; Heart Research UK. B.A. Whittam: None. R. Ajjan: Consultant; Self; Abbott. Research Support; Self; Abbott, LifeScan, Inc." @default.
- W2948442936 created "2019-06-14" @default.
- W2948442936 creator A5010413733 @default.
- W2948442936 creator A5035588730 @default.
- W2948442936 creator A5054745036 @default.
- W2948442936 creator A5057822188 @default.
- W2948442936 creator A5082491938 @default.
- W2948442936 creator A5086223086 @default.
- W2948442936 date "2019-06-01" @default.
- W2948442936 modified "2023-09-24" @default.
- W2948442936 title "283-OR: Structured Nurse-Led Intervention following Ambulance Call Out for Hypoglycemia Reduces Cardiovascular Mortality in Type 2 Diabetes" @default.
- W2948442936 doi "https://doi.org/10.2337/db19-283-or" @default.
- W2948442936 hasPublicationYear "2019" @default.
- W2948442936 type Work @default.
- W2948442936 sameAs 2948442936 @default.
- W2948442936 citedByCount "0" @default.
- W2948442936 crossrefType "journal-article" @default.
- W2948442936 hasAuthorship W2948442936A5010413733 @default.
- W2948442936 hasAuthorship W2948442936A5035588730 @default.
- W2948442936 hasAuthorship W2948442936A5054745036 @default.
- W2948442936 hasAuthorship W2948442936A5057822188 @default.
- W2948442936 hasAuthorship W2948442936A5082491938 @default.
- W2948442936 hasAuthorship W2948442936A5086223086 @default.
- W2948442936 hasConcept C134018914 @default.
- W2948442936 hasConcept C159110408 @default.
- W2948442936 hasConcept C194828623 @default.
- W2948442936 hasConcept C2777180221 @default.
- W2948442936 hasConcept C2780665704 @default.
- W2948442936 hasConcept C2780668416 @default.
- W2948442936 hasConcept C545542383 @default.
- W2948442936 hasConcept C555293320 @default.
- W2948442936 hasConcept C71924100 @default.
- W2948442936 hasConceptScore W2948442936C134018914 @default.
- W2948442936 hasConceptScore W2948442936C159110408 @default.
- W2948442936 hasConceptScore W2948442936C194828623 @default.
- W2948442936 hasConceptScore W2948442936C2777180221 @default.
- W2948442936 hasConceptScore W2948442936C2780665704 @default.
- W2948442936 hasConceptScore W2948442936C2780668416 @default.
- W2948442936 hasConceptScore W2948442936C545542383 @default.
- W2948442936 hasConceptScore W2948442936C555293320 @default.
- W2948442936 hasConceptScore W2948442936C71924100 @default.
- W2948442936 hasIssue "Supplement 1" @default.
- W2948442936 hasLocation W29484429361 @default.
- W2948442936 hasOpenAccess W2948442936 @default.
- W2948442936 hasPrimaryLocation W29484429361 @default.
- W2948442936 hasRelatedWork W1563850031 @default.
- W2948442936 hasRelatedWork W2015926965 @default.
- W2948442936 hasRelatedWork W2233866314 @default.
- W2948442936 hasRelatedWork W2415759662 @default.
- W2948442936 hasRelatedWork W2534023429 @default.
- W2948442936 hasRelatedWork W2805857714 @default.
- W2948442936 hasRelatedWork W2983693063 @default.
- W2948442936 hasRelatedWork W3036934084 @default.
- W2948442936 hasRelatedWork W3152935002 @default.
- W2948442936 hasRelatedWork W4322723668 @default.
- W2948442936 hasVolume "68" @default.
- W2948442936 isParatext "false" @default.
- W2948442936 isRetracted "false" @default.
- W2948442936 magId "2948442936" @default.
- W2948442936 workType "article" @default.