Matches in SemOpenAlex for { <https://semopenalex.org/work/W2948445485> ?p ?o ?g. }
- W2948445485 abstract "Brain is well known for its multifarious nature and complicated diseases. Brain consists of natural barriers that pose difficulty for the therapeutic agents to reach the brain tissues. Blood-brain barrier is the major barrier while blood-brain tumor barrier, blood-cerebrospinal (CSF) barrier and efflux pump impart additional hindrance. Therapeutic goal is to achieve a considerable drug concentration in the brain tissues in order to obtain desired therapeutic outcomes. To overcome the barriers, nanotechnology was employed in the field of drug delivery and brain targeting. Nanopharmaceuticals are rapidly emerging sub-branch that deals with the drug-loaded nanocarriers or nanomaterials that have unique physicochemical properties and minute size range for penetrating the CNS. Additionally, nanopharmaceuticals can be tailored with functional modalities to achieve active targeting to the brain tissues. The magic behind their therapeutic success is the reduced amount of dose and lesser toxicity, whereby localizing the therapeutic agent to the specific site. Different types of nanopharmaceuticals like polymeric, lipidic and amphiphilic nanocarriers were administered into the living organisms by exploiting different routes for improved targeted therapy. Therefore, it is essential to throw light on the properties, mechanism and delivery route of the major nanopharmaceuticals that are employed for the brain-specific drug delivery." @default.
- W2948445485 created "2019-06-14" @default.
- W2948445485 creator A5017148337 @default.
- W2948445485 creator A5029897975 @default.
- W2948445485 creator A5042336792 @default.
- W2948445485 creator A5084844290 @default.
- W2948445485 creator A5090259754 @default.
- W2948445485 date "2020-02-05" @default.
- W2948445485 modified "2023-10-07" @default.
- W2948445485 title "Nanopharmaceuticals: A Boon to the Brain-Targeted Drug Delivery" @default.
- W2948445485 cites W1171315567 @default.
- W2948445485 cites W1482904772 @default.
- W2948445485 cites W1528488968 @default.
- W2948445485 cites W1608424455 @default.
- W2948445485 cites W1714678118 @default.
- W2948445485 cites W1796054280 @default.
- W2948445485 cites W1823348626 @default.
- W2948445485 cites W1966187612 @default.
- W2948445485 cites W1966720603 @default.
- W2948445485 cites W1967083835 @default.
- W2948445485 cites W1968235575 @default.
- W2948445485 cites W1977332519 @default.
- W2948445485 cites W1978075794 @default.
- W2948445485 cites W1980110116 @default.
- W2948445485 cites W1982413610 @default.
- W2948445485 cites W1983486698 @default.
- W2948445485 cites W1983818104 @default.
- W2948445485 cites W1991300039 @default.
- W2948445485 cites W1996098147 @default.
- W2948445485 cites W1998302888 @default.
- W2948445485 cites W2005397347 @default.
- W2948445485 cites W2007003442 @default.
- W2948445485 cites W2009798263 @default.
- W2948445485 cites W2013280216 @default.
- W2948445485 cites W2013585426 @default.
- W2948445485 cites W2014202811 @default.
- W2948445485 cites W2019126236 @default.
- W2948445485 cites W2021946861 @default.
- W2948445485 cites W2025486324 @default.
- W2948445485 cites W2025531839 @default.
- W2948445485 cites W2025585924 @default.
- W2948445485 cites W2025595011 @default.
- W2948445485 cites W2034335918 @default.
- W2948445485 cites W2034588313 @default.
- W2948445485 cites W2035270319 @default.
- W2948445485 cites W2035536790 @default.
- W2948445485 cites W2036932527 @default.
- W2948445485 cites W2037932639 @default.
- W2948445485 cites W2040882015 @default.
- W2948445485 cites W2041748108 @default.
- W2948445485 cites W2042295385 @default.
- W2948445485 cites W2042935377 @default.
- W2948445485 cites W2045651730 @default.
- W2948445485 cites W2047936567 @default.
- W2948445485 cites W2049479334 @default.
- W2948445485 cites W2055928970 @default.
- W2948445485 cites W2056272101 @default.
- W2948445485 cites W2058865733 @default.
- W2948445485 cites W2060255956 @default.
- W2948445485 cites W2061225714 @default.
- W2948445485 cites W2064910464 @default.
- W2948445485 cites W2068203421 @default.
- W2948445485 cites W2069726112 @default.
- W2948445485 cites W2071438575 @default.
- W2948445485 cites W2071926235 @default.
- W2948445485 cites W2073672966 @default.
- W2948445485 cites W2075337839 @default.
- W2948445485 cites W2075347200 @default.
- W2948445485 cites W2076493179 @default.
- W2948445485 cites W2088441058 @default.
- W2948445485 cites W2090677413 @default.
- W2948445485 cites W2091250479 @default.
- W2948445485 cites W2091322268 @default.
- W2948445485 cites W2092108048 @default.
- W2948445485 cites W2093918270 @default.
- W2948445485 cites W2094264010 @default.
- W2948445485 cites W2094641772 @default.
- W2948445485 cites W2095340988 @default.
- W2948445485 cites W2112007587 @default.
- W2948445485 cites W2124627567 @default.
- W2948445485 cites W2135278595 @default.
- W2948445485 cites W2140181820 @default.
- W2948445485 cites W2141710697 @default.
- W2948445485 cites W2142073291 @default.
- W2948445485 cites W2149946337 @default.
- W2948445485 cites W2168221883 @default.
- W2948445485 cites W2223036396 @default.
- W2948445485 cites W2316829396 @default.
- W2948445485 cites W2395300225 @default.
- W2948445485 cites W2398068955 @default.
- W2948445485 cites W2463417777 @default.
- W2948445485 cites W2503365563 @default.
- W2948445485 cites W2568630644 @default.
- W2948445485 cites W2595922933 @default.
- W2948445485 cites W2789535394 @default.
- W2948445485 cites W2790852710 @default.
- W2948445485 cites W2799675103 @default.
- W2948445485 cites W4239022189 @default.
- W2948445485 cites W4248107770 @default.
- W2948445485 cites W966257 @default.