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• W2948735145 abstract "Glucocorticoids are potent anti-inflammatory agents that are commonly used in the treatment of various glomerular diseases. Data from in vitro and in vivo studies, in both animals and humans, convincingly demonstrate that glucocorticoids have many beneficial direct effects on glomeruli, including podocytes, suggesting that, in theory, systemic administration is not necessary to achieve therapeutic benefit. Indeed, it is increasingly recognized that systemic steroids often have an unfavorable risk-to-benefit ratio. As we move into an age of personalized medicine, strategies to develop targeted steroid delivery systems and individualized risk assessment algorithms are desirable in clinicians’ efforts to “first, do no harm.”" @default.
• W2948735145 created "2019-06-14" @default.
• W2948735145 creator A5010521322 @default.
• W2948735145 date "2019-07-01" @default.
• W2948735145 modified "2023-09-27" @default.
• W2948735145 title "Role of the glucocorticoid receptor in glomerular disease" @default.
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• W2948735145 doi "https://doi.org/10.1152/ajprenal.00217.2019" @default.
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