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• W2948740739 endingPage "218" @default.
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• W2948740739 abstract "Subjective well-being (SWB) is closely related to our physical and mental health. Existing studies show that neural or genetic basis underpins individual difference in SWB. Moreover, researchers have found high enrichment of SWB-related mutations in the central nervous system, but the relationship between the genetic architecture of SWB and brain morphology has not been explored. Considering the polygenic nature of SWB, in this study, we aim to establish a measure of additive genetic effect on SWB and explore its relationship to the brain anatomical structure. Based on the results of genome-wide association study (GWAS) on SWB, the polygenic scores (PGSs) of SWB at eight different thresholds were calculated in a large Chinese sample (N = 585). Then, we analyzed the associations between the PGSs of SWB and cortical thickness (CT) or gray matter volume (GMV) measured from 3.0-T structural imaging data. In whole-brain analyses, we found that a higher PGS was significantly associated with increased CT in the right superior temporal gyrus (STG) and GMV in the right insula, both of which are involved in social cognition and emotional processing. More importantly, these findings were repeatable at some different thresholds. The results may suggest that the brain morphology of right STG and insula is partly regulated by SWB-related genetic factors." @default.
• W2948740739 created "2019-06-14" @default.
• W2948740739 creator A5003783734 @default.
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• W2948740739 date "2019-08-01" @default.
• W2948740739 modified "2023-10-17" @default.
• W2948740739 title "Polygenic Score of Subjective Well-Being Is Associated with the Brain Morphology in Superior Temporal Gyrus and Insula" @default.
• W2948740739 cites W1192488478 @default.
• W2948740739 cites W1677152310 @default.
• W2948740739 cites W1681270005 @default.
• W2948740739 cites W1967252619 @default.
• W2948740739 cites W1975359614 @default.
• W2948740739 cites W1980406651 @default.
• W2948740739 cites W1987320610 @default.
• W2948740739 cites W1989334446 @default.
• W2948740739 cites W1992338409 @default.
• W2948740739 cites W1992656413 @default.
• W2948740739 cites W1996925265 @default.
• W2948740739 cites W2013146000 @default.
• W2948740739 cites W2018333256 @default.
• W2948740739 cites W2019308227 @default.
• W2948740739 cites W2029967713 @default.
• W2948740739 cites W2032639509 @default.
• W2948740739 cites W2041005250 @default.
• W2948740739 cites W2041978052 @default.
• W2948740739 cites W2043834761 @default.
• W2948740739 cites W2044289130 @default.
• W2948740739 cites W2045589228 @default.
• W2948740739 cites W2055876609 @default.
• W2948740739 cites W2070808447 @default.
• W2948740739 cites W2075757370 @default.
• W2948740739 cites W2098597355 @default.
• W2948740739 cites W2101357408 @default.
• W2948740739 cites W2101518034 @default.
• W2948740739 cites W2103326489 @default.
• W2948740739 cites W2103546211 @default.
• W2948740739 cites W2105558714 @default.
• W2948740739 cites W2107790366 @default.
• W2948740739 cites W2108169091 @default.
• W2948740739 cites W2113737964 @default.
• W2948740739 cites W2116529202 @default.
• W2948740739 cites W2116947810 @default.
• W2948740739 cites W2118196858 @default.
• W2948740739 cites W2118798035 @default.
• W2948740739 cites W2120159226 @default.
• W2948740739 cites W2121184942 @default.
• W2948740739 cites W2125002529 @default.
• W2948740739 cites W2127259621 @default.
• W2948740739 cites W2128095563 @default.
• W2948740739 cites W2128104774 @default.
• W2948740739 cites W2129598810 @default.
• W2948740739 cites W2132135247 @default.
• W2948740739 cites W2134929000 @default.
• W2948740739 cites W2141496952 @default.
• W2948740739 cites W2143742215 @default.
• W2948740739 cites W2155707407 @default.
• W2948740739 cites W2157752701 @default.
• W2948740739 cites W2157805769 @default.
• W2948740739 cites W2161633633 @default.
• W2948740739 cites W2163186714 @default.
• W2948740739 cites W2164568585 @default.
• W2948740739 cites W2178774099 @default.
• W2948740739 cites W2180721625 @default.
• W2948740739 cites W2283621774 @default.
• W2948740739 cites W2336993262 @default.
• W2948740739 cites W2409715846 @default.
• W2948740739 cites W2510973425 @default.
• W2948740739 cites W2520791202 @default.
• W2948740739 cites W2732740969 @default.
• W2948740739 cites W2736536999 @default.
• W2948740739 cites W2752312334 @default.
• W2948740739 cites W2761320504 @default.
• W2948740739 cites W2762265603 @default.
• W2948740739 cites W2784273558 @default.
• W2948740739 cites W2791458050 @default.
• W2948740739 cites W2811019266 @default.
• W2948740739 cites W2883573930 @default.
• W2948740739 cites W2977883299 @default.
• W2948740739 cites W3122170055 @default.
• W2948740739 cites W3122997891 @default.
• W2948740739 cites W4230046771 @default.
• W2948740739 cites W4230353308 @default.
• W2948740739 cites W4236725577 @default.
• W2948740739 cites W4241074797 @default.
• W2948740739 cites W4243414629 @default.
• W2948740739 cites W4366807502 @default.
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• W2948740739 doi "https://doi.org/10.1016/j.neuroscience.2019.05.055" @default.
• W2948740739 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31173807" @default.
• W2948740739 hasPublicationYear "2019" @default.
• W2948740739 type Work @default.

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