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- W2948745080 abstract "Diclofenac (DIC) is a non-steroidal anti-inflammatory drug of wide use around the world. Electroanalytical methods display a high analytical potential for application in pharmaceutical samples but the drawbacks concerning electrode fouling and reproducibility are of major concern. Henceforth, the aim of this work was to propose the use of alternative low-cost carbon black (CB) and ionic liquid (IL) matrix to modify the surface of pencil graphite electrodes (PGE) in order to quantify DIC in raw materials, intermediates, and final products, as well as in stability assays of tablets. The proposed method using CB+IL/PGE displayed good recovery (99.4%) as well as limits of detection (LOD) of 0.08 µmol L-1 and limits of quantification (LOQ) of 0.28 µmol L−1. CB+IL/PGE response was five times greater than the unmodified PGE. CB+IL-PGE stands as an interesting alternative for DIC assessment in different pharmaceutical samples." @default.
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- W2948745080 date "2019-06-04" @default.
- W2948745080 modified "2023-09-23" @default.
- W2948745080 title "Voltammetric Evaluation of Diclofenac Tablets Samples through Carbon Black-Based Electrodes" @default.
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- W2948745080 doi "https://doi.org/10.3390/ph12020083" @default.
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