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- W2948804037 abstract "Introduction: Cerebral amyloidoma is a rare form of amyloidosis with localized tumor like amyloid deposition in the brain composed of insoluble fibrillary protein with cross beta sheet conformation. Its usual presentation includes vision loss, seizures, behavioral changes, cognitive decline and recurrent headaches. It has a benign course with a slow progression and it is not associated with dissemination. Case report: We report a case of a 65-year-old Caucasian woman who presented with symptoms of progressively worsening cognitive dysfunction of 6 months’ duration. On computed tomography of the brain, she had a right frontal and left parietal hemorrhagic mass with a large amount of vasogenic edema and a midline shift. MRI showed heterogeneously enhancing hemorrhagic of 5.2 × 2.6 × 3.6 cm in size, with a satellite lesion. Initially, this was suspected to be a high grade glioma vs. hemorrhagic metastatic lesions. She underwent stereotactic biopsy of the mass and histopathology was consistent with cerebral amyloidoma with marked IgA lambda plasma cell differentiation. She did not have any evidence of systemic amyloidosis and therefore, she is being clinically observed with a regular follow up and annual CT surveillance. She has remained stable over the past 2 years, although she has residual cognitive dysfunction. Conclusion: Cerebral amyloidoma can mimic malignant central nervous system neoplasms and should be considered as a differential of any single or multiple mass lesions occurring in the white matter region of the brain with a characteristic appearance of “hyper dense lesions” on computed tomography. It is a benign disease with no metastatic potential, that usually resolves completely after resection." @default.
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- W2948804037 date "2019-01-01" @default.
- W2948804037 modified "2023-09-22" @default.
- W2948804037 title "A Rare Case of CerebralAmyloidoma Mimicking aHemorrhagic Malignant CNS Neoplasm: A Case Report" @default.
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