FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2949053103> ?p ?o ?g. }

• W2949053103 endingPage "K27" @default.
• W2949053103 startingPage "K21" @default.
• W2949053103 abstract "Prolactinomas are the most commonly encountered pituitary adenomas in the clinical setting. While most can be controlled by dopamine agonists, a subset of prolactinomas are dopamine-resistant and very aggressive. In such tumors, the treatment of choice is neurosurgery and radiotherapy, with or without temozolomide. Here, we report a patient with an highly aggressive, dopamine-resistant prolactinoma, who only achieved biochemical and tumor control during pasireotide long-acting release (PAS-LAR) therapy, a second-generation somatostatin receptor ligand (SRL). Interestingly, cystic degeneration, tumor cell necrosis or both was observed after PAS-LAR administration suggesting an antitumor effect. This case shows that PAS-LAR therapy holds clinical potential in selective aggressive, dopamine-resistant prolactinomas that express somatostatin (SST) receptor subtype 5 and appears to be a potential new treatment option before starting temozolomide. In addition, PAS-LAR therapy may induce cystic degeneration, tumor cell necrosis or both in prolactinomas." @default.
• W2949053103 created "2019-06-14" @default.
• W2949053103 creator A5006066076 @default.
• W2949053103 creator A5024586979 @default.
• W2949053103 creator A5058109283 @default.
• W2949053103 creator A5059257320 @default.
• W2949053103 creator A5061346627 @default.
• W2949053103 creator A5061789966 @default.
• W2949053103 creator A5073100093 @default.
• W2949053103 creator A5075512837 @default.
• W2949053103 creator A5088396121 @default.
• W2949053103 creator A5091051936 @default.
• W2949053103 date "2019-08-01" @default.
• W2949053103 modified "2023-10-15" @default.
• W2949053103 title "Excellent response to pasireotide therapy in an aggressive and dopamine-resistant prolactinoma" @default.
• W2949053103 cites W1974190969 @default.
• W2949053103 cites W2007440241 @default.
• W2949053103 cites W2008727195 @default.
• W2949053103 cites W2012451298 @default.
• W2949053103 cites W2017283375 @default.
• W2949053103 cites W2028190688 @default.
• W2949053103 cites W2038440391 @default.
• W2949053103 cites W2123338693 @default.
• W2949053103 cites W2135614796 @default.
• W2949053103 cites W2136861429 @default.
• W2949053103 cites W2245508602 @default.
• W2949053103 cites W2286538107 @default.
• W2949053103 cites W2340386540 @default.
• W2949053103 cites W2406886408 @default.
• W2949053103 cites W2935406275 @default.
• W2949053103 cites W2931142169 @default.
• W2949053103 doi "https://doi.org/10.1530/eje-19-0279" @default.
• W2949053103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31167168" @default.
• W2949053103 hasPublicationYear "2019" @default.
• W2949053103 type Work @default.
• W2949053103 sameAs 2949053103 @default.
• W2949053103 citedByCount "35" @default.
• W2949053103 countsByYear W29490531032019 @default.
• W2949053103 countsByYear W29490531032020 @default.
• W2949053103 countsByYear W29490531032021 @default.
• W2949053103 countsByYear W29490531032022 @default.
• W2949053103 countsByYear W29490531032023 @default.
• W2949053103 crossrefType "journal-article" @default.
• W2949053103 hasAuthorship W2949053103A5006066076 @default.
• W2949053103 hasAuthorship W2949053103A5024586979 @default.
• W2949053103 hasAuthorship W2949053103A5058109283 @default.
• W2949053103 hasAuthorship W2949053103A5059257320 @default.
• W2949053103 hasAuthorship W2949053103A5061346627 @default.
• W2949053103 hasAuthorship W2949053103A5061789966 @default.
• W2949053103 hasAuthorship W2949053103A5073100093 @default.
• W2949053103 hasAuthorship W2949053103A5075512837 @default.
• W2949053103 hasAuthorship W2949053103A5088396121 @default.
• W2949053103 hasAuthorship W2949053103A5091051936 @default.
• W2949053103 hasBestOaLocation W29490531031 @default.
• W2949053103 hasConcept C120069818 @default.
• W2949053103 hasConcept C126322002 @default.
• W2949053103 hasConcept C134018914 @default.
• W2949053103 hasConcept C143998085 @default.
• W2949053103 hasConcept C2776297358 @default.
• W2949053103 hasConcept C2777389519 @default.
• W2949053103 hasConcept C2777433750 @default.
• W2949053103 hasConcept C2777658017 @default.
• W2949053103 hasConcept C2778918492 @default.
• W2949053103 hasConcept C2779064019 @default.
• W2949053103 hasConcept C2779371878 @default.
• W2949053103 hasConcept C2908910360 @default.
• W2949053103 hasConcept C2984496839 @default.
• W2949053103 hasConcept C44208683 @default.
• W2949053103 hasConcept C509974204 @default.
• W2949053103 hasConcept C513476851 @default.
• W2949053103 hasConcept C71315377 @default.
• W2949053103 hasConcept C71924100 @default.
• W2949053103 hasConcept C80115893 @default.
• W2949053103 hasConceptScore W2949053103C120069818 @default.
• W2949053103 hasConceptScore W2949053103C126322002 @default.
• W2949053103 hasConceptScore W2949053103C134018914 @default.
• W2949053103 hasConceptScore W2949053103C143998085 @default.
• W2949053103 hasConceptScore W2949053103C2776297358 @default.
• W2949053103 hasConceptScore W2949053103C2777389519 @default.
• W2949053103 hasConceptScore W2949053103C2777433750 @default.
• W2949053103 hasConceptScore W2949053103C2777658017 @default.
• W2949053103 hasConceptScore W2949053103C2778918492 @default.
• W2949053103 hasConceptScore W2949053103C2779064019 @default.
• W2949053103 hasConceptScore W2949053103C2779371878 @default.
• W2949053103 hasConceptScore W2949053103C2908910360 @default.
• W2949053103 hasConceptScore W2949053103C2984496839 @default.
• W2949053103 hasConceptScore W2949053103C44208683 @default.
• W2949053103 hasConceptScore W2949053103C509974204 @default.
• W2949053103 hasConceptScore W2949053103C513476851 @default.
• W2949053103 hasConceptScore W2949053103C71315377 @default.
• W2949053103 hasConceptScore W2949053103C71924100 @default.
• W2949053103 hasConceptScore W2949053103C80115893 @default.
• W2949053103 hasIssue "2" @default.
• W2949053103 hasLocation W29490531031 @default.
• W2949053103 hasLocation W29490531032 @default.
• W2949053103 hasLocation W29490531033 @default.
• W2949053103 hasOpenAccess W2949053103 @default.
• W2949053103 hasPrimaryLocation W29490531031 @default.

• next