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• W2949114027 abstract "<h3>Background:</h3> In 1973 Moll and Wright published the first paper on the classification criteria for Psoriatic arthritis (PsA) which included several phenotypes of PsA: Oligoarticular, Polyarticular, axial, DIP, and Mutilans. Whether these subtypes change over time or are related to treatment response is not known. The hypothesis of this study is that with some exceptions, the Moll and Wright subtype classification criteria are stable over time and the pattern may have important therapeutic implications. <h3>Objectives:</h3> The objective of this study was to evaluate the persistence of the Moll and Wright classification criteria in PsA patients. <h3>Methods:</h3> This study is a retrospective chart review of PsA patients seen at a single center between January 1, 2013 and December 31, 2016. The patients in this study were identified using the ICD-9 or ICD-10 codes for PsA and were then classified using the CASPAR classification criteria for psoriatic arthritis. Patients who met CASPAR classification criteria were subsequently sub-classified using the Moll and Wright classification criteria based on the manifestations of PsA at their index outpatient visit. This subtype was then compared to their Moll and Wright subtype at the last outpatient visit prior to January 3, 2019. While it was possible for patients to display more than one subtype simultaneously, the classification made at baseline and at latest visit reflected the predominant Moll and Wright subtype of the patient, in the opinion of the expert treating rheumatologist. <h3>Results:</h3> 76 patients were identified as meeting entry criteria, with none being in remission at the index visit. Mean age of patients at the latest visit was 60.2 ± 12.6 years, and 47.4% were male. Median time between the index visit and latest visit was 7 years [IQR: 5 to 8 years]. 42.1% of patients had the same Moll and Wright subtype at both visits. Table 1 presents the distribution of Moll and Wright subtypes present at index visit and latest visit. Table 2 reports the changes, or lack thereof, in subtype between visits. 22/76 patients (28.9%) were in remission at the latest visit. Of the patients in remission, 12 (54.5%) were being treated with a biologic, DMARD, and/or steroid. <h3>Conclusion:</h3> In this retrospective analysis there was a persistence of Moll and Wright subtype in 42.1% of psoriatic arthritis patients over the median time of 7 years. Whether patients who maintain Moll and Wright subtypes respond differently to targeted therapy for PsA should be evaluated in prospective trials. <h3>References</h3> [1] Moll J. M. H., Wright V. Psoriatic arthritis. Semin arthritis Rheum. 1973; 3(1): 55-78. <h3>Disclosure of interests:</h3> None declared" @default.
• W2949114027 created "2019-06-27" @default.
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• W2949114027 date "2019-06-01" @default.
• W2949114027 modified "2023-09-26" @default.
• W2949114027 title "AB0780 PERSISTENCE OF MOLL AND WRIGHT CLASSIFICATION CRITERIA OVER TIME" @default.
• W2949114027 doi "https://doi.org/10.1136/annrheumdis-2019-eular.5586" @default.
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