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- W2949145629 abstract "New benzo[f]chromen-1-one derivatives were prepared by a sequence of reactions starting from appropriate 1-(2,3-dihydroxynaphthalen-1-yl)ethanone. The prepared target compounds were confirmedupon correct elemental analysis and spectroscopic data. Compounds were evaluated as antioxidant agents using DPPH assay and ascorbic acid was used as a reference drug. Compounds 3 (inhibitive concentration (IC 50 ) = 0.0013 mg/mL), 7 (IC 50 = 0.013 mg/mL) and 10 (IC 50 = 0.0166 mg/mL) have the best activities higher than ascorbic acid, in which compound 3 is the best antioxidant agent. The prepared compounds were evaluated as antibacterial agents against Gram (+)- and Gram (-)-bacterial strainsusing streptomycin as a reference drug. In general, most the tested compounds are considered as potent antioxidant and antibacterial agents compared to standard substances. Compound 3 exhibited the highest antibacterial activity compared to streptomycin. We hope in future work that compound 3 could be used in drug design for developingnew antioxidant agent with good property." @default.
- W2949145629 created "2019-06-27" @default.
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- W2949145629 date "2017-09-27" @default.
- W2949145629 modified "2023-09-23" @default.
- W2949145629 title "Efficient Synthesis of Some Benzochromenone Analogues as Potential Novel Antioxidant and Antimicrobial Agents" @default.
- W2949145629 hasPublicationYear "2017" @default.
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