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• W2949170147 abstract "ABSTRACT Across metazoans, visual systems employ different types of photoreceptor neurons to detect light. These include rhabdomeric PRs, which exist in distantly related phyla and possess an evolutionarily conserved phototransduction cascade. While the development of rhabdomeric PRs has been thoroughly studied in the fruit fly Drosophila melanogaster , we still know very little about how they form in other species. To investigate this question, we tested whether the transcription factor Glass, which is crucial for instructing rhabdomeric PR formation in Drosophila , may play a similar role in other metazoans. Glass homologues exist throughout the animal kingdom, indicating that this protein evolved prior to the metazoan radiation. Interestingly, our work indicates that glass is not expressed in rhabdomeric photoreceptors in the planarian Schmidtea mediterranea nor in the annelid Platynereis dumerilii . Combined with a comparative analysis of the Glass DNA-binding domain, our data suggest that the fate of rhabdomeric PRs is controlled by Glass-dependent and Glass-independent mechanisms in different animal clades." @default.
• W2949170147 created "2019-06-27" @default.
• W2949170147 creator A5001119999 @default.
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• W2949170147 date "2018-10-17" @default.
• W2949170147 modified "2023-10-03" @default.
• W2949170147 title "Glass confers rhabdomeric photoreceptor identity in<i>Drosophila</i>, but not across all metazoans" @default.
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• W2949170147 doi "https://doi.org/10.1101/446161" @default.
• W2949170147 hasPublicationYear "2018" @default.
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