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• W2949171475 abstract "We present SoptSC, a similarity matrix optimization method for single-cell data analysis, which performs clustering, pseudotemporal ordering, lineage and marker gene identification from a cell similarity matrix. SoptSC also presents a new function: cell-cell signaling network inference, enabling the reconstruction of complex lineage relationships and associated feed- back/feedforward interactions. As we show by application to several datasets, SoptSC can predict the number of clusters and the initial state unsupervised, and outperforms current methods for inference of clusters and pseudotime from single-cell data." @default.
• W2949171475 created "2019-06-27" @default.
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• W2949171475 date "2018-05-12" @default.
• W2949171475 modified "2023-09-24" @default.
• W2949171475 title "SoptSC: Similarity matrix optimization for clustering, lineage, and signaling inference" @default.
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