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• W2949192305 abstract "Passaluriasis is a common infestation of lagomorphs, which clinically manifests in intense itching around the anus, various disorders of digestion and loss of weight. We performed a study of infested rabbits of the seryi veleten breed, which were kept in individual farms in Poltava Oblast (Ukraine). During the autopsy, in the cavity of the large intestine, there were found small, spindle-like helminths of white colour. Out of 10 rabbits, 846 nematodes were extracted (369 males and 477 females, identified as Passalurus ambiguus (Rudolphi, 1819) Dujardin, 1845. It was determined that the extensity of infestation in female rabbits reached 56.4%, male rabbits – 43.6%. The results of metric parameters of the nematodes are as follows: mean body length of males equaled 4.6 ± 0.4, females – 9.7 ± 1.21 mm, and maximum width – 257.4 ± 17.8 and 546.2 ± 37.1 µm respectively. A common feature of mature nematodes of this species is the presence of a rounded extension (bulbus) at the end of the esophagus. During chronic course of passaluriasis in rabbits, pathomorphological changes developed in the large intestine. The upper epithelium of the large intestine was damaged in some places, certain epithelian cells were found in the lumen of the intestine. The intestinal glands are widened, filled with slimy content of mostly dark blue-violet colour, especially in the upper sections of the glands. In the deep sections of the glands, slime was almost transparent. In deep sections of the glands the slime was almost transparent. In the epithelium cells of the glands, slimy granules were also of basophilic colour. The muscularis mucosae of the mucous membrane, especially between the intestinal glands was swollen, had practically no colour, the collagen fibers were stretched, thinned-out. Edemas were also recorded in the tela submucosa. In some preparations, the muscularis mucosae was notably infiltrated by lymphoid cells and histiocytes. On large extensions, we found some signs of hypersecretion of slime in goblet cells of the intestinal glands as accumulations of granules of slime in the cytoplasm, which had poorly developed colouration. On the side of the muscular and serous membranes, no pathological changes were found. The information presented here indicates the relevance of passaluriasis infestation as an etiological factor of occurrence of chronic catarrhal colitis with lymphohistiocytosis." @default.
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• W2949192305 date "2019-02-27" @default.
• W2949192305 modified "2023-10-02" @default.
• W2949192305 title "Pathomorphological changes in the large intestine of rabbits parasitised by Passalurus ambiguus (Nematoda, Oxyuridae)" @default.
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• W2949192305 doi "https://doi.org/10.15421/021911" @default.
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