FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2949270733> ?p ?o ?g. }

• W2949270733 endingPage "10274" @default.
• W2949270733 startingPage "10263" @default.
• W2949270733 abstract "The asymmetric synthesis of functionalized homoallylic amines and silyl functionalized pyrrolidines through the Lewis acid promoted condensation of chiral (E)-crotylsilanes with sulfonyl imines and in situ generated N-acyl imines is described. We had anticipated that this bond construction could be used in the asymmetric synthesis of the N-terminal amino acid subunit of the nikkomycins. Aryl sulfonyl imines condense with chiral silane reagents in the presence of BF3·OEt2 to form homoallylic arylsulfonyl amines with useful levels of syn selectivity. For cases involving aryl N-acyl imines we have learned that the temperature controls the course of the reaction. For instance, at temperatures of −78°C or below the major product is the pyrrolidine, while at higher temperatures (−30 to −20°C) the homoallylic amine is produced. For the cases studied, the [3+2]-annulation is limited to aryl imine derivatives, as alkyl- and branched- imines failed to produce the pyrrolidine derivatives: higher reaction temperatures promote the conversion of the annulation product to the homoallylic amines. In double stereodifferentiating reactions with in situ generated imines, good levels of selectivity were achieved in the formation of secondary amines bearing syn–anti and syn–syn stereochemical triads." @default.
• W2949270733 created "2019-06-27" @default.
• W2949270733 creator A5019647387 @default.
• W2949270733 creator A5024083619 @default.
• W2949270733 creator A5026064774 @default.
• W2949270733 date "2000-12-01" @default.
• W2949270733 modified "2023-10-16" @default.
• W2949270733 title "Asymmetric Synthesis of Homoallylic Amines and Functionalized Pyrrolidines via Direct Amino-Crotylation of In Situ Generated Imines" @default.
• W2949270733 cites W1980416100 @default.
• W2949270733 cites W1990818859 @default.
• W2949270733 cites W1991892874 @default.
• W2949270733 cites W2000230039 @default.
• W2949270733 cites W2002778997 @default.
• W2949270733 cites W2006397961 @default.
• W2949270733 cites W2009472524 @default.
• W2949270733 cites W2011471385 @default.
• W2949270733 cites W2012658004 @default.
• W2949270733 cites W2015051247 @default.
• W2949270733 cites W2017312962 @default.
• W2949270733 cites W2021989945 @default.
• W2949270733 cites W2028590822 @default.
• W2949270733 cites W2039078809 @default.
• W2949270733 cites W2040718816 @default.
• W2949270733 cites W2043554130 @default.
• W2949270733 cites W2047175063 @default.
• W2949270733 cites W2057717450 @default.
• W2949270733 cites W2069607377 @default.
• W2949270733 cites W2074632092 @default.
• W2949270733 cites W2086684339 @default.
• W2949270733 cites W2098811525 @default.
• W2949270733 cites W2129360049 @default.
• W2949270733 cites W2949097172 @default.
• W2949270733 cites W2951004861 @default.
• W2949270733 cites W2951098533 @default.
• W2949270733 cites W2951100933 @default.
• W2949270733 cites W2951685811 @default.
• W2949270733 cites W2952852554 @default.
• W2949270733 cites W2952927800 @default.
• W2949270733 cites W3005275105 @default.
• W2949270733 cites W3023532348 @default.
• W2949270733 cites W4238136596 @default.
• W2949270733 doi "https://doi.org/10.1016/s0040-4020(00)00870-x" @default.
• W2949270733 hasPublicationYear "2000" @default.
• W2949270733 type Work @default.
• W2949270733 sameAs 2949270733 @default.
• W2949270733 citedByCount "42" @default.
• W2949270733 countsByYear W29492707332012 @default.
• W2949270733 countsByYear W29492707332013 @default.
• W2949270733 countsByYear W29492707332014 @default.
• W2949270733 countsByYear W29492707332015 @default.
• W2949270733 countsByYear W29492707332018 @default.
• W2949270733 countsByYear W29492707332020 @default.
• W2949270733 countsByYear W29492707332021 @default.
• W2949270733 countsByYear W29492707332022 @default.
• W2949270733 countsByYear W29492707332023 @default.
• W2949270733 crossrefType "journal-article" @default.
• W2949270733 hasAuthorship W2949270733A5019647387 @default.
• W2949270733 hasAuthorship W2949270733A5024083619 @default.
• W2949270733 hasAuthorship W2949270733A5026064774 @default.
• W2949270733 hasConcept C118792377 @default.
• W2949270733 hasConcept C131779359 @default.
• W2949270733 hasConcept C146686406 @default.
• W2949270733 hasConcept C155647269 @default.
• W2949270733 hasConcept C161790260 @default.
• W2949270733 hasConcept C163638829 @default.
• W2949270733 hasConcept C178790620 @default.
• W2949270733 hasConcept C185592680 @default.
• W2949270733 hasConcept C21951064 @default.
• W2949270733 hasConcept C2776573223 @default.
• W2949270733 hasConcept C2778851528 @default.
• W2949270733 hasConcept C2780263894 @default.
• W2949270733 hasConcept C2781076698 @default.
• W2949270733 hasConcept C67524406 @default.
• W2949270733 hasConcept C7512685 @default.
• W2949270733 hasConcept C87906975 @default.
• W2949270733 hasConceptScore W2949270733C118792377 @default.
• W2949270733 hasConceptScore W2949270733C131779359 @default.
• W2949270733 hasConceptScore W2949270733C146686406 @default.
• W2949270733 hasConceptScore W2949270733C155647269 @default.
• W2949270733 hasConceptScore W2949270733C161790260 @default.
• W2949270733 hasConceptScore W2949270733C163638829 @default.
• W2949270733 hasConceptScore W2949270733C178790620 @default.
• W2949270733 hasConceptScore W2949270733C185592680 @default.
• W2949270733 hasConceptScore W2949270733C21951064 @default.
• W2949270733 hasConceptScore W2949270733C2776573223 @default.
• W2949270733 hasConceptScore W2949270733C2778851528 @default.
• W2949270733 hasConceptScore W2949270733C2780263894 @default.
• W2949270733 hasConceptScore W2949270733C2781076698 @default.
• W2949270733 hasConceptScore W2949270733C67524406 @default.
• W2949270733 hasConceptScore W2949270733C7512685 @default.
• W2949270733 hasConceptScore W2949270733C87906975 @default.
• W2949270733 hasIssue "52" @default.
• W2949270733 hasLocation W29492707331 @default.
• W2949270733 hasOpenAccess W2949270733 @default.
• W2949270733 hasPrimaryLocation W29492707331 @default.
• W2949270733 hasRelatedWork W1752945975 @default.
• W2949270733 hasRelatedWork W2003357490 @default.
• W2949270733 hasRelatedWork W2038014986 @default.

• next