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- W2949284298 abstract "A scaleable and highly regioselective C-4 bromination of 5-substituted oxazoles is described. The use of DMF as solvent played a critical role in significantly improving the C-4/C-2 bromination ratio. The resulting 4-bromooxazoles were shown to be good Suzuki–Miyaura coupling partners with arylboronic acids. Furthermore, a simple and convenient method that employs triethylamine efficiently purged residual levels of palladium and iron to less than 10 ppm." @default.
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- W2949284298 date "2007-10-19" @default.
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- W2949284298 title "Syntheses of 4,5-Disubstituted Oxazoles via Regioselective C-4 Bromination" @default.
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- W2949284298 doi "https://doi.org/10.1021/op700176n" @default.
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