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- W2949312501 abstract "Abstract A simple, mild, and efficient one-pot method for the synthesis of substituted 2-aminothiazoles has been reported. The reaction involves the formation of sulfenyl bromide as an umpolung intermediate of nucleophilic sulfur, which is responsible for C–S bond formation leading to oxidative cyclization of ketones and thioureas to furnish the desired products. Carbon tetrabromide was used as a convenient and mild brominating reagent under basic condition at room temperature to give 2-aminothiazoles in good to excellent yields." @default.
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- W2949312501 date "2015-10-01" @default.
- W2949312501 modified "2023-10-18" @default.
- W2949312501 title "Carbon tetrabromide mediated oxidative cyclocondensation of ketones and thioureas: an easy access to 2-aminothiazoles" @default.
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- W2949312501 doi "https://doi.org/10.1016/j.tetlet.2015.08.064" @default.
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