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- W2949406013 abstract "Two new rearranged limonoids, harperforatin (1) and harperfolide (2), and a new chromone, harperamone (3), were isolated from fruits and roots of Harrisonia perforata, together with eight known compounds. Their structures were elucidated on the basis of spectroscopic data. Harperfolide (2) exhibited potent anti-inflammatory activity by suppressing nitric oxide (NO) production from activated macrophages with IC50 value of 6.51 μM. Furthermore, its effect is mediated by reduction of iNOS protein expression, attributable to the inhibitory action of LPS-induced NO production." @default.
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- W2949406013 date "2013-07-01" @default.
- W2949406013 modified "2023-10-03" @default.
- W2949406013 title "Rearranged limonoids and chromones from Harrisonia perforata and their anti-inflammatory activity" @default.
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- W2949406013 doi "https://doi.org/10.1016/j.bmcl.2013.04.064" @default.
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