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- W2949407046 abstract "Abstract As part of our investigation into the development of potent and selective human β 3 agonists, a series of thiazolidinedione analogues was prepared and evaluated for their biological activity on the human β 3 -adrenergic receptor. The oxadiazolidinedione derivative 17 was found to be the most potent and selective compound in this study, with an EC 50 value of 0.02 μM at the β 3 receptor, 259-fold selectivity over the β 1 receptor, and 745-fold selectivity over the β 2 receptor." @default.
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- W2949407046 date "2010-05-25" @default.
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- W2949407046 title "ChemInform Abstract: New Oxadiazolidinedione Derivatives as Potent and Selective Human β3 Agonists." @default.
- W2949407046 cites W2024618068 @default.
- W2949407046 doi "https://doi.org/10.1002/chin.200132242" @default.
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