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- W2949410267 abstract "The preparation of new analogues of 5-alkynyl- and 5-alkenyl-uracil is described. The synthesis involved palladium-catalyzed C-C coupling reactions, with the 5-ethynyl, 5-(1-hexynyl), and 5-(2-phenylethynyl) derivatives prepared through a Sonogashira coupling. A Stille coupling reaction was used to obtain the 5-(1-hexynyl) derivative, whilst the (E)-5-(2-bromovinyl) derivative was prepared using the Heck reaction. All the methods were clean and simple to perform." @default.
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- W2949410267 date "2006-12-01" @default.
- W2949410267 modified "2023-10-16" @default.
- W2949410267 title "Palladium-Catalyzed Approach to 1,2-Disubstituted Carbocyclic Nucleoside Analogues of 5-Alkynyl and 5-Alkenyl Uracil" @default.
- W2949410267 doi "https://doi.org/10.1055/s-2006-950334" @default.
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