FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2949446051> ?p ?o ?g. }

• W2949446051 abstract "Background Systemic sclerosis (SSc) is characterized by stiffness and contraction of tissues, which leads to a limitation in the execution of day-to-day activities. The aim of our study was to investigate the impact of specialized physical-occupational therapy (POT) focused on the hands/face and QoL of SSc patients. Objectives Fifty five patients fulfilled the EULAR/ACR criteria for SSc and had skin involvement leading to hand/face function impairment. 25 patients were recruited into the intervention group (IG) and 30 patients into the control group (CG). Both groups received an educational material for home exercise, but only the IG underwent a 6-month intervention with a subsequent 6-month follow-up period. Methods Patients were assessed by a physician and a physiotherapist blinded to intervention at months 0, 3, 6, and 12. Patients also filled out patient reported outcomes questionnaires and provided blood for routine laboratory analysis and bio-banking. Data analysis was done between groups and within the group. Results Compared to the observed statistically significant deterioration in the CG, we found a statistically significant improvement in the IG in objectively assessed function and strength of hand, distance between incisors and functional ability (SHAQ) (Table). Only numerical improvements in the IG during the intervention compared to numerical deterioration in CG that did not reach statistical significance were observed in subjectively assessed hand function and mouth handicap, functional ability (HAQ) and in some domains of QoL (SF-36) and fatigue (FIS – cognitive function). During the follow-up period, there was a significant deterioration or stagnation of the achieved positive results in the IG. Conclusion Our program led to a significant improvement in the observed parameters that was clinically significant in a substantial proportion of patients, and prevention of the expected worsening of hand/face handicap and QoL. Acknowledgement Supported by AZV-16-33574A, SVV for FTVS UK 2019-260466, MHCR 023728. Disclosure of Interests Maja Spiritovic: None declared, Hana Smucrova: None declared, Sabina Oreska: None declared, Hana Storkanova: None declared, Barbora Heřmankova: None declared, Petr Cesak: None declared, Adela Rathouska: None declared, Olga Růžickova: None declared, Karel Pavelka: None declared, Ladislav Senolt Grant/research support from: AbbVie, Consultant for: AbbVie, Bristol-Myers Squibb, Celgene Corporation, Merck Sharp and Dohme, Novartis, Pfizer, Roche, UCB, Amgen, Takeda, Speakers bureau: AbbVie, Amgen, Bristol-Myers Squibb, Celgene Corporation, Eli Lilly, Merck Sharp and Dohme, Novartis, Pfizer, Roche, UCB, Jiři Vencovský Consultant for: Samsung, Speakers bureau: AbbVie, Novartis, Pfizer, Sanofi, Eli Lilly, Biogen, UCB, MSD, Werfen, Roche, Radim Becvař Consultant for: consultancy Actelion, Michal Tomcik: None declared" @default.
• W2949446051 created "2019-06-27" @default.
• W2949446051 creator A5019621028 @default.
• W2949446051 creator A5031588644 @default.
• W2949446051 creator A5045563364 @default.
• W2949446051 creator A5046574378 @default.
• W2949446051 creator A5048881704 @default.
• W2949446051 creator A5057948163 @default.
• W2949446051 creator A5059312680 @default.
• W2949446051 creator A5062096932 @default.
• W2949446051 creator A5064499724 @default.
• W2949446051 creator A5069564967 @default.
• W2949446051 creator A5077144593 @default.
• W2949446051 creator A5079921904 @default.
• W2949446051 creator A5089477356 @default.
• W2949446051 date "2019-06-01" @default.
• W2949446051 modified "2023-09-26" @default.
• W2949446051 title "OP0066 EFFECTIVENESS OF SPECIALIZED HAND/FACE PHYSICAL-OCCUPATIONAL THERAPY IN PATIENTS WITH SYSTEMIC SCLEROSIS – PRELIMINARY RESULTS OF A ONE-YEAR CONTROLLED STUDY" @default.
• W2949446051 doi "https://doi.org/10.1136/annrheumdis-2019-eular.4630" @default.
• W2949446051 hasPublicationYear "2019" @default.
• W2949446051 type Work @default.
• W2949446051 sameAs 2949446051 @default.
• W2949446051 citedByCount "0" @default.
• W2949446051 crossrefType "proceedings-article" @default.
• W2949446051 hasAuthorship W2949446051A5019621028 @default.
• W2949446051 hasAuthorship W2949446051A5031588644 @default.
• W2949446051 hasAuthorship W2949446051A5045563364 @default.
• W2949446051 hasAuthorship W2949446051A5046574378 @default.
• W2949446051 hasAuthorship W2949446051A5048881704 @default.
• W2949446051 hasAuthorship W2949446051A5057948163 @default.
• W2949446051 hasAuthorship W2949446051A5059312680 @default.
• W2949446051 hasAuthorship W2949446051A5062096932 @default.
• W2949446051 hasAuthorship W2949446051A5064499724 @default.
• W2949446051 hasAuthorship W2949446051A5069564967 @default.
• W2949446051 hasAuthorship W2949446051A5077144593 @default.
• W2949446051 hasAuthorship W2949446051A5079921904 @default.
• W2949446051 hasAuthorship W2949446051A5089477356 @default.
• W2949446051 hasBestOaLocation W29494460511 @default.
• W2949446051 hasConcept C102190203 @default.
• W2949446051 hasConcept C126322002 @default.
• W2949446051 hasConcept C159110408 @default.
• W2949446051 hasConcept C1862650 @default.
• W2949446051 hasConcept C2779951463 @default.
• W2949446051 hasConcept C71924100 @default.
• W2949446051 hasConceptScore W2949446051C102190203 @default.
• W2949446051 hasConceptScore W2949446051C126322002 @default.
• W2949446051 hasConceptScore W2949446051C159110408 @default.
• W2949446051 hasConceptScore W2949446051C1862650 @default.
• W2949446051 hasConceptScore W2949446051C2779951463 @default.
• W2949446051 hasConceptScore W2949446051C71924100 @default.
• W2949446051 hasLocation W29494460511 @default.
• W2949446051 hasOpenAccess W2949446051 @default.
• W2949446051 hasPrimaryLocation W29494460511 @default.
• W2949446051 hasRelatedWork W2108110322 @default.
• W2949446051 hasRelatedWork W2411931116 @default.
• W2949446051 hasRelatedWork W2412981802 @default.
• W2949446051 hasRelatedWork W2551902274 @default.
• W2949446051 hasRelatedWork W2554908598 @default.
• W2949446051 hasRelatedWork W2755287240 @default.
• W2949446051 hasRelatedWork W2808644801 @default.
• W2949446051 hasRelatedWork W2895642842 @default.
• W2949446051 hasRelatedWork W2899817624 @default.
• W2949446051 hasRelatedWork W2909462925 @default.
• W2949446051 hasRelatedWork W2950694353 @default.
• W2949446051 hasRelatedWork W2950971351 @default.
• W2949446051 hasRelatedWork W2952193797 @default.
• W2949446051 hasRelatedWork W2952909301 @default.
• W2949446051 hasRelatedWork W2953377481 @default.
• W2949446051 hasRelatedWork W3034980018 @default.
• W2949446051 hasRelatedWork W3047874896 @default.
• W2949446051 hasRelatedWork W3164740964 @default.
• W2949446051 hasRelatedWork W3164950654 @default.
• W2949446051 hasRelatedWork W3165695314 @default.
• W2949446051 isParatext "false" @default.
• W2949446051 isRetracted "false" @default.
• W2949446051 magId "2949446051" @default.
• W2949446051 workType "article" @default.