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• W2949468657 abstract "Objective The aim of this study was to analyze myopericytoma in the oral and maxillofacial region in terms of clinical appearance, diagnosis, treatment, and outcomes. Study Design Data on 5 new patients with myopericytoma in the oral and maxillofacial region treated at our department were collected and analyzed. Results There were 2 males and 3 females (age range 10–62 years; mean age 43.8 years). All of the 5 patients presented with masses showing benign biologic behavior. Imaging examinations with use of computed tomography or magnetic resonance imaging showed heterogeneous regions with internal contrast-enhancement or cystic change in 3 cases. All of the patients underwent surgery. Histologic examination showed a broad morphologic spectrum characterized by concentric and perivascular growth of ovoid, plump spindled, and/or round myoid tumor cells. Immunohistochemical examination showed positive staining for vimentin and smooth muscle actin, and negative for CD34 and desmin. During the follow-up period (8–56 months), there was no tumor recurrence. Conclusions Myopericytoma in the oral and maxillofacial region always exhibits benign biologic behavior and a heterogeneous region with internal contrast-enhancement or cystic change on imaging examinations. Surgery is the first choice of treatment and results in good clinical outcomes. The aim of this study was to analyze myopericytoma in the oral and maxillofacial region in terms of clinical appearance, diagnosis, treatment, and outcomes. Data on 5 new patients with myopericytoma in the oral and maxillofacial region treated at our department were collected and analyzed. There were 2 males and 3 females (age range 10–62 years; mean age 43.8 years). All of the 5 patients presented with masses showing benign biologic behavior. Imaging examinations with use of computed tomography or magnetic resonance imaging showed heterogeneous regions with internal contrast-enhancement or cystic change in 3 cases. All of the patients underwent surgery. Histologic examination showed a broad morphologic spectrum characterized by concentric and perivascular growth of ovoid, plump spindled, and/or round myoid tumor cells. Immunohistochemical examination showed positive staining for vimentin and smooth muscle actin, and negative for CD34 and desmin. During the follow-up period (8–56 months), there was no tumor recurrence. Myopericytoma in the oral and maxillofacial region always exhibits benign biologic behavior and a heterogeneous region with internal contrast-enhancement or cystic change on imaging examinations. Surgery is the first choice of treatment and results in good clinical outcomes." @default.
• W2949468657 created "2019-06-27" @default.
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• W2949468657 date "2019-10-01" @default.
• W2949468657 modified "2023-10-17" @default.
• W2949468657 title "Clinical and pathologic analysis of myopericytoma in the oral and maxillofacial region" @default.
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• W2949468657 doi "https://doi.org/10.1016/j.oooo.2019.06.004" @default.
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