FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2949483519> ?p ?o ?g. }

• W2949483519 endingPage "180" @default.
• W2949483519 startingPage "175" @default.
• W2949483519 abstract "Expression of the latent membrane protein-1 (LMP1) of Epstein-Barr virus (EBV) was investigated in 153 cases of EBV+ classic Hodgkin lymphoma (cHL); 120 cases were pediatric patients (< 14 years of age) from Iraq, and 33 cases were adult patients from Italy. We describe for the first time the presence of LMP1 protein in EBV-encoded RNA (EBER)-negative follicular dendritic cells (FDCs) of reactive germinal centers (GC) associated with EBV+ cHL. Presence of LMP1+ GCs was independent of geographic region and age of patients. Variable numbers of reactive GCs were present in 22.2% of cases (34 of 153), whereas LMP1 staining of FDCs was present in about a third of cases (10 of 34) with reactive GC. Most cases with LMP1+ GC were mixed-cellularity (MC) subtype, but some nodular sclerosis (NS) was also present. GC cells with LMP1+ FDCs were surrounded by numerous EBV-infected cells which were positive for EBER, LMP1, and CD30. Double immunolocalization analysis revealed that LMP1 was associated with CD63, an exosomal marker, and with CD21. The possibility is discussed that peri-follicular EBV-infected cells release LMP1 protein, perhaps through exosomes, and that the protein is then captured by FDCs and is presented to EBER-negative GC B cells." @default.
• W2949483519 created "2019-06-27" @default.
• W2949483519 creator A5000603010 @default.
• W2949483519 creator A5024364275 @default.
• W2949483519 creator A5024414993 @default.
• W2949483519 creator A5025046387 @default.
• W2949483519 creator A5053263340 @default.
• W2949483519 creator A5058649415 @default.
• W2949483519 creator A5061762183 @default.
• W2949483519 creator A5079758476 @default.
• W2949483519 creator A5088581133 @default.
• W2949483519 date "2019-06-15" @default.
• W2949483519 modified "2023-10-14" @default.
• W2949483519 title "Follicular dendritic cells display microvesicle-associated LMP1 in reactive germinal centers of EBV+ classic Hodgkin lymphoma" @default.
• W2949483519 cites W1485544797 @default.
• W2949483519 cites W1595961517 @default.
• W2949483519 cites W1941864838 @default.
• W2949483519 cites W1988699093 @default.
• W2949483519 cites W1991226842 @default.
• W2949483519 cites W1999358473 @default.
• W2949483519 cites W2040305776 @default.
• W2949483519 cites W2057154903 @default.
• W2949483519 cites W2057332675 @default.
• W2949483519 cites W2086932055 @default.
• W2949483519 cites W2144454093 @default.
• W2949483519 cites W2159278398 @default.
• W2949483519 cites W2159333075 @default.
• W2949483519 cites W2569150814 @default.
• W2949483519 cites W2617572075 @default.
• W2949483519 cites W2753945613 @default.
• W2949483519 cites W2800377469 @default.
• W2949483519 cites W2885335758 @default.
• W2949483519 cites W2891794117 @default.
• W2949483519 doi "https://doi.org/10.1007/s00428-019-02605-w" @default.
• W2949483519 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6647529" @default.
• W2949483519 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31203443" @default.
• W2949483519 hasPublicationYear "2019" @default.
• W2949483519 type Work @default.
• W2949483519 sameAs 2949483519 @default.
• W2949483519 citedByCount "11" @default.
• W2949483519 countsByYear W29494835192021 @default.
• W2949483519 countsByYear W29494835192022 @default.
• W2949483519 countsByYear W29494835192023 @default.
• W2949483519 crossrefType "journal-article" @default.
• W2949483519 hasAuthorship W2949483519A5000603010 @default.
• W2949483519 hasAuthorship W2949483519A5024364275 @default.
• W2949483519 hasAuthorship W2949483519A5024414993 @default.
• W2949483519 hasAuthorship W2949483519A5025046387 @default.
• W2949483519 hasAuthorship W2949483519A5053263340 @default.
• W2949483519 hasAuthorship W2949483519A5058649415 @default.
• W2949483519 hasAuthorship W2949483519A5061762183 @default.
• W2949483519 hasAuthorship W2949483519A5079758476 @default.
• W2949483519 hasAuthorship W2949483519A5088581133 @default.
• W2949483519 hasBestOaLocation W29494835191 @default.
• W2949483519 hasConcept C104317684 @default.
• W2949483519 hasConcept C142724271 @default.
• W2949483519 hasConcept C145059251 @default.
• W2949483519 hasConcept C159047783 @default.
• W2949483519 hasConcept C159654299 @default.
• W2949483519 hasConcept C196166836 @default.
• W2949483519 hasConcept C203014093 @default.
• W2949483519 hasConcept C20518536 @default.
• W2949483519 hasConcept C2522874641 @default.
• W2949483519 hasConcept C2776090121 @default.
• W2949483519 hasConcept C2778453870 @default.
• W2949483519 hasConcept C2779338263 @default.
• W2949483519 hasConcept C2780430958 @default.
• W2949483519 hasConcept C2781375147 @default.
• W2949483519 hasConcept C2909763251 @default.
• W2949483519 hasConcept C2992779791 @default.
• W2949483519 hasConcept C3753494 @default.
• W2949483519 hasConcept C553184892 @default.
• W2949483519 hasConcept C55493867 @default.
• W2949483519 hasConcept C67662055 @default.
• W2949483519 hasConcept C70905583 @default.
• W2949483519 hasConcept C71924100 @default.
• W2949483519 hasConcept C86803240 @default.
• W2949483519 hasConcept C8891405 @default.
• W2949483519 hasConcept C96926380 @default.
• W2949483519 hasConceptScore W2949483519C104317684 @default.
• W2949483519 hasConceptScore W2949483519C142724271 @default.
• W2949483519 hasConceptScore W2949483519C145059251 @default.
• W2949483519 hasConceptScore W2949483519C159047783 @default.
• W2949483519 hasConceptScore W2949483519C159654299 @default.
• W2949483519 hasConceptScore W2949483519C196166836 @default.
• W2949483519 hasConceptScore W2949483519C203014093 @default.
• W2949483519 hasConceptScore W2949483519C20518536 @default.
• W2949483519 hasConceptScore W2949483519C2522874641 @default.
• W2949483519 hasConceptScore W2949483519C2776090121 @default.
• W2949483519 hasConceptScore W2949483519C2778453870 @default.
• W2949483519 hasConceptScore W2949483519C2779338263 @default.
• W2949483519 hasConceptScore W2949483519C2780430958 @default.
• W2949483519 hasConceptScore W2949483519C2781375147 @default.
• W2949483519 hasConceptScore W2949483519C2909763251 @default.
• W2949483519 hasConceptScore W2949483519C2992779791 @default.
• W2949483519 hasConceptScore W2949483519C3753494 @default.
• W2949483519 hasConceptScore W2949483519C553184892 @default.
• W2949483519 hasConceptScore W2949483519C55493867 @default.

• next