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- W2949508046 abstract "The R- and S-enantiomers of 2-[[hydroxyl[[2-[(octadecyloxy) methyl]tetrahydrofuran-2-yl]methoxy]-phosphinyl]oxy]-N,N,N,- trimethylethylaminium hydroxide salt (SRI 62-834) have been evaluated in several assays to determine potential antitumor activity. The S-enantiomer showed slightly greater cytotoxic activity than the R- or RS-forms against several murine tumor cell lines. In the mouse Meth A fibrosarcoma model, the S-enantiomer was ca. 4 times more effective than the R-isomer in controlling size of tumor growth and increasing the number of survivors." @default.
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- W2949508046 date "1996-01-01" @default.
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- W2949508046 title "Antitumor Activity of the<i>R</i>- and<i>S</i>-Enantiomers of<i>RS</i>-2-[[Hydroxy[[2-[(octadecyloxy)methyl]tetrahydrofuran-2-yl]methoxy]phosphinyl]oxy]-<i>N</i>,<i>N</i>,<i>N</i>-trimethylethylaminium Hydroxide Inner Salt" @default.
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- W2949508046 doi "https://doi.org/10.1021/jm950072e" @default.
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