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- W2949521663 abstract "Abstract Investigation of the terrestrial Streptomyces sp. BCC27095 led to the isolation of two new ( 1 and 2 ) and two known ( 3 and 5 ) anthraquinone derivatives along with the previously reported compound, steffimycin B ( 4 ). The chemical structures were determined on the basis of NMR spectroscopic data. These compounds exhibited significant antimalarial (against Plasmodium falciparum , K-1 multidrug resistant strain) and antimycobacterial (against Mycobacterium tuberculosis H37Ra) activities with IC 50 values in the range of 0.32–3.20 μg/mL and MIC in a range of 0.0031–1.56 μg/mL, respectively. They were also evaluated for antibacterial activity against Bacillus cereus and for cytotoxicity against both malignant (MCF-7, KB, NCI-H187) and non-malignant (Vero) cells." @default.
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- W2949521663 date "2016-03-01" @default.
- W2949521663 modified "2023-09-27" @default.
- W2949521663 title "ChemInform Abstract: Antimalarial and Antimycobacterial Agents from Streptomyces sp. BCC27095" @default.
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- W2949521663 doi "https://doi.org/10.1002/chin.201614209" @default.
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