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• W2949530948 abstract "An efficient stereoselective synthesis of Z-stilbenes has been developed from diarylalkynes via a new hydrosilylation–protodesilylation process. The scope and limitation of this method is presented to stereoselectively prepare a wide range of (Z)-stilbenes in a one-pot way is presented. A concise application to the preparation of combretastatin A-4 (CA-4), a vascular targeting agent inhibitor of tubulin polymerisation is described." @default.
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• W2949530948 date "2008-02-01" @default.
• W2949530948 modified "2023-10-15" @default.
• W2949530948 title "One-pot hydrosilylation–protodesilylation of functionalized diarylalkynes: a highly selective access to Z-stilbenes. Application to the synthesis of combretastatin A-4" @default.
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• W2949530948 doi "https://doi.org/10.1016/j.tetlet.2007.12.057" @default.
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