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• W2949537557 startingPage "2883" @default.
• W2949537557 abstract "A novel indirect electrochemical approach is reported to improve the sensitivity of Hg2+ quantification in environmental water samples. This strategy is based on the Hg2+ induced selective interaction of thymine mismatched pairs in a thymine-rich aptamer DNA to improve the specificity, while template-independent terminal deoxynucleotidyl transferase (TdT) extended the 3′-OH aptamer termini with repeated bases and increased the sensitivity. The introduction of the target Hg2+ blocked aptamer extension. Taking advantage of an electrochemical platform, this aptamer-TdT based amplification sensor enabled the specific quantification of Hg2+ ion over a wide linear range from 2 pM to 20 nM with a low limit of detection equal to 0.1 pM. The proposed strategy is promising for the detection of other metal ions." @default.
• W2949537557 created "2019-06-27" @default.
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• W2949537557 date "2019-06-12" @default.
• W2949537557 modified "2023-10-17" @default.
• W2949537557 title "Electrochemical amplification for Hg(II) quantification by anchoring an enzymatically extended aptamer" @default.
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• W2949537557 doi "https://doi.org/10.1080/00032719.2019.1626415" @default.
• W2949537557 hasPublicationYear "2019" @default.
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