FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2949546957> ?p ?o ?g. }

• W2949546957 endingPage "245" @default.
• W2949546957 startingPage "236" @default.
• W2949546957 abstract "OBJECTIVE Craniopharyngioma represents up to 10% of pediatric brain tumors. Although these lesions are benign, attempts at gross-total resection (GTR) can lead to serious complications. More conservative approaches have emerged but require adjuvant radiation. Endoscopic endonasal surgery (EES) aimed at GTR has the potential to result in fewer complications, but there has been limited comparison to open surgery. The authors performed a review of these two approaches within their institution to elucidate potential benefits and complication differences. METHODS The authors performed a retrospective review of pediatric patients undergoing resection of craniopharyngioma at their institution between 2001 and 2017. Volumetric analysis of tumor size and postoperative ischemic injury was performed. Charts were reviewed for a number of outcome measures. RESULTS A total of 43 patients with an average age of 8.2 years were identified. Open surgery was the initial intervention in 15 and EES in 28. EES was performed in patients 3–17 years of age. EES has been the only approach used since 2011. In the entire cohort, GTR was more common in the EES group (85.7% vs 53.3%, p = 0.03). Recurrence rate (40% vs 14.2%, p = 0.13) and need for adjuvant radiation (20.0% vs 10.7%, p = 0.71) were higher in the open surgical group, although not statistically significant. Pseudoaneurysm development was only observed in the open surgical group. Volumetric imaging analysis showed a trend toward larger preoperative tumor volumes in the open surgical group, so a matched cohort analysis was performed with the largest tumors from the EES group. This revealed no difference in residual tumor volume (p = 0.28), but the volume of postoperative ischemia was still significantly larger in the open group (p = 0.004). Postoperative weight gain was more common in the open surgical group, a statistically significant finding in the complete patient group that trended toward significance in the matched cohort groups. Body mass index at follow-up correlated with volume of ischemic injury in regression analysis of the complete patient cohort (p = 0.05). CONCLUSIONS EES was associated with similar, if not better, extent of resection and significantly less ischemic injury than open surgery. Pseudoaneurysms were only seen in the open surgical group. Weight gain was also less prevalent in the EES cohort and appears be correlated with extent of ischemic injury at time of surgery." @default.
• W2949546957 created "2019-06-27" @default.
• W2949546957 creator A5011723619 @default.
• W2949546957 creator A5011973581 @default.
• W2949546957 creator A5012536194 @default.
• W2949546957 creator A5015841662 @default.
• W2949546957 creator A5016696075 @default.
• W2949546957 creator A5018178422 @default.
• W2949546957 creator A5018440805 @default.
• W2949546957 creator A5027109682 @default.
• W2949546957 creator A5052948685 @default.
• W2949546957 creator A5065213881 @default.
• W2949546957 creator A5067659279 @default.
• W2949546957 creator A5074348750 @default.
• W2949546957 creator A5084042057 @default.
• W2949546957 date "2019-09-01" @default.
• W2949546957 modified "2023-10-09" @default.
• W2949546957 title "Endoscopic endonasal resection versus open surgery for pediatric craniopharyngioma: comparison of outcomes and complications" @default.
• W2949546957 cites W1224836924 @default.
• W2949546957 cites W1483634231 @default.
• W2949546957 cites W1484372212 @default.
• W2949546957 cites W1543182320 @default.
• W2949546957 cites W1551719856 @default.
• W2949546957 cites W1963726941 @default.
• W2949546957 cites W1974805133 @default.
• W2949546957 cites W1976809318 @default.
• W2949546957 cites W1990793682 @default.
• W2949546957 cites W1993753281 @default.
• W2949546957 cites W2004189261 @default.
• W2949546957 cites W2028838806 @default.
• W2949546957 cites W2035105771 @default.
• W2949546957 cites W2039489347 @default.
• W2949546957 cites W2048099175 @default.
• W2949546957 cites W2049978781 @default.
• W2949546957 cites W2051343719 @default.
• W2949546957 cites W2052088413 @default.
• W2949546957 cites W2060338846 @default.
• W2949546957 cites W2090331475 @default.
• W2949546957 cites W2092024769 @default.
• W2949546957 cites W2113022073 @default.
• W2949546957 cites W2129672209 @default.
• W2949546957 cites W2135540260 @default.
• W2949546957 cites W2142328984 @default.
• W2949546957 cites W2148596299 @default.
• W2949546957 cites W2160002747 @default.
• W2949546957 cites W2295495114 @default.
• W2949546957 cites W2342581388 @default.
• W2949546957 cites W2748800262 @default.
• W2949546957 cites W2767819299 @default.
• W2949546957 cites W2794832014 @default.
• W2949546957 cites W2904123285 @default.
• W2949546957 cites W2908860883 @default.
• W2949546957 cites W4210986102 @default.
• W2949546957 cites W4211228754 @default.
• W2949546957 cites W4236286461 @default.
• W2949546957 cites W4245392732 @default.
• W2949546957 doi "https://doi.org/10.3171/2019.4.peds18612" @default.
• W2949546957 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31174192" @default.
• W2949546957 hasPublicationYear "2019" @default.
• W2949546957 type Work @default.
• W2949546957 sameAs 2949546957 @default.
• W2949546957 citedByCount "36" @default.
• W2949546957 countsByYear W29495469572018 @default.
• W2949546957 countsByYear W29495469572019 @default.
• W2949546957 countsByYear W29495469572020 @default.
• W2949546957 countsByYear W29495469572021 @default.
• W2949546957 countsByYear W29495469572022 @default.
• W2949546957 countsByYear W29495469572023 @default.
• W2949546957 crossrefType "journal-article" @default.
• W2949546957 hasAuthorship W2949546957A5011723619 @default.
• W2949546957 hasAuthorship W2949546957A5011973581 @default.
• W2949546957 hasAuthorship W2949546957A5012536194 @default.
• W2949546957 hasAuthorship W2949546957A5015841662 @default.
• W2949546957 hasAuthorship W2949546957A5016696075 @default.
• W2949546957 hasAuthorship W2949546957A5018178422 @default.
• W2949546957 hasAuthorship W2949546957A5018440805 @default.
• W2949546957 hasAuthorship W2949546957A5027109682 @default.
• W2949546957 hasAuthorship W2949546957A5052948685 @default.
• W2949546957 hasAuthorship W2949546957A5065213881 @default.
• W2949546957 hasAuthorship W2949546957A5067659279 @default.
• W2949546957 hasAuthorship W2949546957A5074348750 @default.
• W2949546957 hasAuthorship W2949546957A5084042057 @default.
• W2949546957 hasConcept C126322002 @default.
• W2949546957 hasConcept C141071460 @default.
• W2949546957 hasConcept C167135981 @default.
• W2949546957 hasConcept C2777047896 @default.
• W2949546957 hasConcept C71924100 @default.
• W2949546957 hasConcept C72563966 @default.
• W2949546957 hasConcept C81182388 @default.
• W2949546957 hasConceptScore W2949546957C126322002 @default.
• W2949546957 hasConceptScore W2949546957C141071460 @default.
• W2949546957 hasConceptScore W2949546957C167135981 @default.
• W2949546957 hasConceptScore W2949546957C2777047896 @default.
• W2949546957 hasConceptScore W2949546957C71924100 @default.
• W2949546957 hasConceptScore W2949546957C72563966 @default.
• W2949546957 hasConceptScore W2949546957C81182388 @default.
• W2949546957 hasIssue "3" @default.
• W2949546957 hasLocation W29495469571 @default.

• next