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- W2949553681 abstract "Abstract New indolactam derivatives (2 2–4 7) with a fluorine, bromine, iodine or methyl group at position 6 of (−)-indolactam-V (1) were synthesized from corresponding seco-compounds (6-substituted N-methyl- l -valyl- l -tryptophanols) by the microbial conversion using Streptoverticillium blastmyceticum NA34-17. (−)-5-Fluoroindolactam-V (2 3) and (−)-7-methylindolactam-V (2 8) were similarly obtained by this method. (−)-6-Methylindolactam-V (2 7) had almost the same biological activities as (−)-7-methylindolactam-V (2 8), indicating that the substituent effect at position 6 of (−)-indolactam-V (1) is similar to that at position 7." @default.
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- W2949553681 date "1995-05-01" @default.
- W2949553681 modified "2023-09-23" @default.
- W2949553681 title "Synthesis of 6-substituted indolactams by microbial conversion" @default.
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- W2949553681 doi "https://doi.org/10.1016/0040-4020(95)00298-m" @default.
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