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• W2949568360 abstract "Viral infections in the respiratory tract can cause severe disease and are responsible for a majority of pediatric hospitalizations. Molecular diagnostics have revealed that approximately 20% of these patients are infected by more than one unrelated viral pathogen. To understand how viral coinfection affects disease severity, we inoculated mice with a mild viral pathogen (rhinovirus or murine coronavirus), followed 2 days later by a virulent viral pathogen (influenza A virus). This model demonstrated that rhinovirus can reduce the severity of influenza A virus, which corresponded with an early but controlled inflammatory response in the lungs and early clearance of influenza A virus. We further determined the dose and timing parameters that were important for effective disease attenuation and showed that influenza disease is also reduced by coinfection with a murine coronavirus. These findings demonstrate that coinfecting viruses can alter immune responses and pathogenesis in the respiratory tract." @default.
• W2949568360 created "2019-06-27" @default.
• W2949568360 creator A5010586821 @default.
• W2949568360 creator A5015947005 @default.
• W2949568360 creator A5047096678 @default.
• W2949568360 creator A5050827042 @default.
• W2949568360 date "2018-12-01" @default.
• W2949568360 modified "2023-10-16" @default.
• W2949568360 title "Attenuation of Influenza A Virus Disease Severity by Viral Coinfection in a Mouse Model" @default.
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• W2949568360 cites W1910644139 @default.
• W2949568360 cites W1914585871 @default.
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• W2949568360 cites W1980428624 @default.
• W2949568360 cites W1983483525 @default.
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• W2949568360 cites W1988071414 @default.
• W2949568360 cites W1989088567 @default.
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• W2949568360 cites W2046296199 @default.
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• W2949568360 cites W2053796616 @default.
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• W2949568360 cites W2065445260 @default.
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• W2949568360 cites W2107286925 @default.
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• W2949568360 cites W2265194791 @default.
• W2949568360 cites W2267315119 @default.
• W2949568360 cites W2329486704 @default.
• W2949568360 cites W2337739154 @default.
• W2949568360 cites W2511706616 @default.
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• W2949568360 cites W2569800351 @default.
• W2949568360 cites W2584597755 @default.
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• W2949568360 doi "https://doi.org/10.1128/jvi.00881-18" @default.
• W2949568360 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6232468" @default.
• W2949568360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30232180" @default.
• W2949568360 hasPublicationYear "2018" @default.
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