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- W2949593820 abstract "The enantiomerically pure (S)-5-(tosylmethyl)-2-pyrrolidinone 2, prepared from commercially available (S)-pyroglutaminol, is dialkylated at the nitrogen atom and the α-sulfonyl position using several dielectrophiles using sodium hydride as the base to diastereoselectively afford indolizidine derivatives 5 and the less common hexahydropyrrolo[1,2-a]azepin-3-one 6 in moderate to good yield. This domino process has been applied to the synthesis of (−)-δ-coniceine." @default.
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- W2949593820 date "2001-08-01" @default.
- W2949593820 modified "2023-10-16" @default.
- W2949593820 title "Convergent asymmetric synthesis of indolizidines from (S)-5-(tosylmethyl)-2-pyrrolidinone: synthesis of (−)-δ-coniceine" @default.
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- W2949593820 doi "https://doi.org/10.1016/s0957-4166(01)00377-9" @default.
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