FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2949640552> ?p ?o ?g. }

• W2949640552 abstract "Obesity is associated with an increase of several metabolic disorders leading to the development of diseases such as type 2 diabetes and cardiovascular disease. This is due in part to the ectopic accumulation of triglycerides in organs that are non-adipose tissues, leading to lipotoxicity. Particularly, in the liver, the accumulation of lipids, mainly of triglycerides, leads to the formation of fatty liver. The accumulation of lipids in skeletal muscle and pancreas associates with insulin resistance and a decrease in insulin secretion, respectively. In addition, it has been suggested that dysbiosis of the gut microbiota can contribute to the process of lipid accumulation in non-adipose tissues, especially in the liver. The aim of the present review is to highlight the mechanisms associated with the development of lipotoxicity, and how with the advances in nutrigenomics, it is now possible to understand the molecular mechanisms by which some nutrients can attenuate the ectopic accumulation of triglycerides in non-adipose tissues. Particularly, we emphasize research conducted on the molecular mechanisms of action of soy protein and some of its isoflavones, and how these can reduce lipotoxicity by preventing the accumulation of lipids in the liver, skeletal muscle, and pancreas, as well as their role on the gut microbiota to attenuate the development of fatty liver. Thus, nutrigenomics is opening new dietary strategies based on several functional foods that can be used to ameliorate the pathologies associated with lipotoxicity." @default.
• W2949640552 created "2019-06-27" @default.
• W2949640552 creator A5007104775 @default.
• W2949640552 creator A5037014500 @default.
• W2949640552 creator A5086409321 @default.
• W2949640552 date "2019-06-11" @default.
• W2949640552 modified "2023-09-26" @default.
• W2949640552 title "Nutrigenomics as a Tool in the Prevention of Lipotoxicity: The Case of Soy Protein" @default.
• W2949640552 cites W1747308264 @default.
• W2949640552 cites W1826616785 @default.
• W2949640552 cites W1964848330 @default.
• W2949640552 cites W1966866971 @default.
• W2949640552 cites W1968417167 @default.
• W2949640552 cites W1975370202 @default.
• W2949640552 cites W1977328678 @default.
• W2949640552 cites W1988865953 @default.
• W2949640552 cites W1996166472 @default.
• W2949640552 cites W2002519246 @default.
• W2949640552 cites W2003072397 @default.
• W2949640552 cites W2010308558 @default.
• W2949640552 cites W2010397464 @default.
• W2949640552 cites W2030610610 @default.
• W2949640552 cites W2035489548 @default.
• W2949640552 cites W2045159219 @default.
• W2949640552 cites W2052002843 @default.
• W2949640552 cites W2053577649 @default.
• W2949640552 cites W2077645437 @default.
• W2949640552 cites W2083126344 @default.
• W2949640552 cites W2090556647 @default.
• W2949640552 cites W2091475986 @default.
• W2949640552 cites W2105532009 @default.
• W2949640552 cites W2107856583 @default.
• W2949640552 cites W2111445543 @default.
• W2949640552 cites W2119901011 @default.
• W2949640552 cites W2126515178 @default.
• W2949640552 cites W2127902558 @default.
• W2949640552 cites W2129456939 @default.
• W2949640552 cites W2132853743 @default.
• W2949640552 cites W2133290655 @default.
• W2949640552 cites W2138628515 @default.
• W2949640552 cites W2141823673 @default.
• W2949640552 cites W2141919149 @default.
• W2949640552 cites W2146544786 @default.
• W2949640552 cites W2148244019 @default.
• W2949640552 cites W2148255071 @default.
• W2949640552 cites W2152877353 @default.
• W2949640552 cites W2159346623 @default.
• W2949640552 cites W2167914776 @default.
• W2949640552 cites W2168471054 @default.
• W2949640552 cites W2169599724 @default.
• W2949640552 cites W2169950424 @default.
• W2949640552 cites W2295433697 @default.
• W2949640552 cites W2298567220 @default.
• W2949640552 cites W2339913955 @default.
• W2949640552 cites W2345368448 @default.
• W2949640552 cites W2524785584 @default.
• W2949640552 cites W2537633102 @default.
• W2949640552 cites W2553807112 @default.
• W2949640552 cites W2602222860 @default.
• W2949640552 cites W2616825195 @default.
• W2949640552 cites W2732099757 @default.
• W2949640552 cites W2736162169 @default.
• W2949640552 cites W2752002135 @default.
• W2949640552 cites W2770903823 @default.
• W2949640552 cites W2775295382 @default.
• W2949640552 cites W2776826800 @default.
• W2949640552 cites W2783761735 @default.
• W2949640552 cites W2800082792 @default.
• W2949640552 cites W2800844816 @default.
• W2949640552 doi "https://doi.org/10.24875/ric.18002843" @default.
• W2949640552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31184331" @default.
• W2949640552 hasPublicationYear "2019" @default.
• W2949640552 type Work @default.
• W2949640552 sameAs 2949640552 @default.
• W2949640552 citedByCount "2" @default.
• W2949640552 countsByYear W29496405522020 @default.
• W2949640552 countsByYear W29496405522021 @default.
• W2949640552 crossrefType "journal-article" @default.
• W2949640552 hasAuthorship W2949640552A5007104775 @default.
• W2949640552 hasAuthorship W2949640552A5037014500 @default.
• W2949640552 hasAuthorship W2949640552A5086409321 @default.
• W2949640552 hasBestOaLocation W29496405521 @default.
• W2949640552 hasConcept C104317684 @default.
• W2949640552 hasConcept C126322002 @default.
• W2949640552 hasConcept C134018914 @default.
• W2949640552 hasConcept C171089720 @default.
• W2949640552 hasConcept C2777391703 @default.
• W2949640552 hasConcept C2779306644 @default.
• W2949640552 hasConcept C44353895 @default.
• W2949640552 hasConcept C55493867 @default.
• W2949640552 hasConcept C71924100 @default.
• W2949640552 hasConcept C86803240 @default.
• W2949640552 hasConcept C97633540 @default.
• W2949640552 hasConceptScore W2949640552C104317684 @default.
• W2949640552 hasConceptScore W2949640552C126322002 @default.
• W2949640552 hasConceptScore W2949640552C134018914 @default.
• W2949640552 hasConceptScore W2949640552C171089720 @default.
• W2949640552 hasConceptScore W2949640552C2777391703 @default.
• W2949640552 hasConceptScore W2949640552C2779306644 @default.
• W2949640552 hasConceptScore W2949640552C44353895 @default.

• next