Matches in SemOpenAlex for { <https://semopenalex.org/work/W2949657931> ?p ?o ?g. }
- W2949657931 endingPage "557" @default.
- W2949657931 startingPage "550" @default.
- W2949657931 abstract "Abstract Wound repair and regeneration is a multidisciplinary field of research with considerable potential value to the management of deep and large burn injuries. These injuries lack an appropriate tissue scaffold and pro-healing cells making them difficult to heal. An alternative to the often limited autologous skin is a therapy that would restore the essential matrix and cellular components for rapid healing. In this study, they use a novel liquid dermal scaffold capable of gelation in vivo to show that it is biocompatible with adipose-derived stem cells. Using a validated method of wound splinting in a delayed-healing murine model, we show that wounds treated with the scaffold and stem cells had a significant reduction in wound size and had accelerated healing compared with control. The wounds treated with stem cells had increased capillary formation, collagen content, epidermal thickness, and essential growth factor expression in the healed tissue compared with control and liquid scaffold alone. This liquid dermal scaffold combined with cells is a feasible treatment strategy for complex or large burn wounds that are otherwise lacking the appropriate cellular matrix necessary for healing." @default.
- W2949657931 created "2019-06-27" @default.
- W2949657931 creator A5011013562 @default.
- W2949657931 creator A5033533579 @default.
- W2949657931 creator A5063403933 @default.
- W2949657931 creator A5079165099 @default.
- W2949657931 creator A5084070344 @default.
- W2949657931 date "2019-06-11" @default.
- W2949657931 modified "2023-10-16" @default.
- W2949657931 title "Liquid Dermal Scaffold With Adipose-Derived Stem Cells Improve Tissue Quality in a Murine Model of Impaired Wound Healing" @default.
- W2949657931 cites W1555423999 @default.
- W2949657931 cites W1943838003 @default.
- W2949657931 cites W1955113987 @default.
- W2949657931 cites W1978482469 @default.
- W2949657931 cites W1982525844 @default.
- W2949657931 cites W2021634519 @default.
- W2949657931 cites W2026271674 @default.
- W2949657931 cites W2029497643 @default.
- W2949657931 cites W2039615721 @default.
- W2949657931 cites W2044738042 @default.
- W2949657931 cites W2053795936 @default.
- W2949657931 cites W2059889165 @default.
- W2949657931 cites W2062172492 @default.
- W2949657931 cites W2063317400 @default.
- W2949657931 cites W2066266876 @default.
- W2949657931 cites W2070863298 @default.
- W2949657931 cites W2109423499 @default.
- W2949657931 cites W2114369369 @default.
- W2949657931 cites W2124857894 @default.
- W2949657931 cites W2133891684 @default.
- W2949657931 cites W2140095796 @default.
- W2949657931 cites W2144337206 @default.
- W2949657931 cites W2146045920 @default.
- W2949657931 cites W2149507412 @default.
- W2949657931 cites W2323254803 @default.
- W2949657931 cites W2350540321 @default.
- W2949657931 cites W2403816514 @default.
- W2949657931 cites W2418913553 @default.
- W2949657931 cites W2519687050 @default.
- W2949657931 cites W2611028868 @default.
- W2949657931 cites W2690794406 @default.
- W2949657931 cites W2746462596 @default.
- W2949657931 cites W2762129585 @default.
- W2949657931 cites W2762342909 @default.
- W2949657931 cites W2791049213 @default.
- W2949657931 cites W2886303209 @default.
- W2949657931 cites W2890139291 @default.
- W2949657931 cites W2895958280 @default.
- W2949657931 cites W2899713320 @default.
- W2949657931 cites W2900142801 @default.
- W2949657931 cites W2902131763 @default.
- W2949657931 cites W2905567844 @default.
- W2949657931 cites W2907406607 @default.
- W2949657931 cites W2913724570 @default.
- W2949657931 cites W2922469030 @default.
- W2949657931 doi "https://doi.org/10.1093/jbcr/irz099" @default.
- W2949657931 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31188436" @default.
- W2949657931 hasPublicationYear "2019" @default.
- W2949657931 type Work @default.
- W2949657931 sameAs 2949657931 @default.
- W2949657931 citedByCount "5" @default.
- W2949657931 countsByYear W29496579312020 @default.
- W2949657931 countsByYear W29496579312021 @default.
- W2949657931 countsByYear W29496579312022 @default.
- W2949657931 crossrefType "journal-article" @default.
- W2949657931 hasAuthorship W2949657931A5011013562 @default.
- W2949657931 hasAuthorship W2949657931A5033533579 @default.
- W2949657931 hasAuthorship W2949657931A5063403933 @default.
- W2949657931 hasAuthorship W2949657931A5079165099 @default.
- W2949657931 hasAuthorship W2949657931A5084070344 @default.
- W2949657931 hasConcept C126322002 @default.
- W2949657931 hasConcept C136229726 @default.
- W2949657931 hasConcept C141071460 @default.
- W2949657931 hasConcept C171056886 @default.
- W2949657931 hasConcept C171089720 @default.
- W2949657931 hasConcept C190567982 @default.
- W2949657931 hasConcept C2780269544 @default.
- W2949657931 hasConcept C28328180 @default.
- W2949657931 hasConcept C49892992 @default.
- W2949657931 hasConcept C71924100 @default.
- W2949657931 hasConcept C86803240 @default.
- W2949657931 hasConcept C89429830 @default.
- W2949657931 hasConcept C95444343 @default.
- W2949657931 hasConceptScore W2949657931C126322002 @default.
- W2949657931 hasConceptScore W2949657931C136229726 @default.
- W2949657931 hasConceptScore W2949657931C141071460 @default.
- W2949657931 hasConceptScore W2949657931C171056886 @default.
- W2949657931 hasConceptScore W2949657931C171089720 @default.
- W2949657931 hasConceptScore W2949657931C190567982 @default.
- W2949657931 hasConceptScore W2949657931C2780269544 @default.
- W2949657931 hasConceptScore W2949657931C28328180 @default.
- W2949657931 hasConceptScore W2949657931C49892992 @default.
- W2949657931 hasConceptScore W2949657931C71924100 @default.
- W2949657931 hasConceptScore W2949657931C86803240 @default.
- W2949657931 hasConceptScore W2949657931C89429830 @default.
- W2949657931 hasConceptScore W2949657931C95444343 @default.
- W2949657931 hasIssue "5" @default.
- W2949657931 hasLocation W29496579311 @default.