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- W2949667110 abstract "The synthesis of methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyran from readily available or commercial o-hydroxybenzaldehydes is described in six steps. The enantiomers of 8-hydroxy-3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyran 1b have been resolved. It is shown that the compound (−)-1b is a more selective D-2 agonist, compared to apomorphine. La synthèse de dérivés hydroxylés et méthoxylés du 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyrane est décrite en six étapes à partir de benzaldéhydes ortho hydroxylés aisément préparables ou commerciaux. La résolution des énantiomères du 8-hydroxy-3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyrane 1b a été réalisée. Comparativement à l'apomorphine, il est montré que le composé (−)-1b est un agoniste plus sélectif des sites D-2." @default.
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- W2949667110 date "1991-07-01" @default.
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- W2949667110 title "Methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyrans: new synthesis and dopaminergic activity" @default.
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- W2949667110 doi "https://doi.org/10.1016/0223-5234(91)90145-d" @default.
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